Analysis of chromatin accessibility in p53 deficient spermatogonial stem cells for high frequency transformation into pluripotent state

OBJECTIVES: Spermatogonial stem cells (SSCs), the germline stem cells (GSCs) committed to spermatogenesis in niche, can transform into pluripotent state in long‐term culture without introduction of exogenous factors, typically in p53 deficiency condition. As the guardian for genomic stability, p53 i...

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Detalles Bibliográficos
Autores principales: Liu, Sitong, Wei, Rui, Liu, Hongyang, Liu, Ruiqi, Li, Pengxiao, Zhang, Xiaoyu, Wei, Wei, Zhao, Xiaodong, Li, Xiaomeng, Yang, Yang, Fu, Xueqi, Zou, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891552/
https://www.ncbi.nlm.nih.gov/pubmed/35119145
http://dx.doi.org/10.1111/cpr.13195

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