Cargando…

In vivo development and single‐cell transcriptome profiling of human brain organoids

OBJECTIVES: Human brain organoids can provide not only promising models for physiological and pathological neurogenesis but also potential therapies in neurological diseases. However, technical issues such as surgical lesions due to transplantation still limit their applications. MATERIALS AND METHO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Shichao, Huang, Fei, Zhang, Huiying, Yang, Yongfeng, Lu, Juan, Chen, Jiadong, Shen, Li, Pei, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891563/ https://www.ncbi.nlm.nih.gov/pubmed/35141969 http://dx.doi.org/10.1111/cpr.13201

Ejemplares similares

Galangin Rescues Alzheimer’s Amyloid-β Induced Mitophagy and Brain Organoid Growth Impairment
por: Zhang, Ru, et al.
Publicado: (2023)

OrganoidDB: a comprehensive organoid database for the multi-perspective exploration of bulk and single-cell transcriptomic profiles of organoids
por: Ma, Qinfeng, et al.
Publicado: (2022)

Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer’s tau pathology
por: Huang, Shichao, et al.
Publicado: (2022)

Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain
por: Tanaka, Yoshiaki, et al.
Publicado: (2020)

Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
por: Fiorenzano, Alessandro, et al.
Publicado: (2021)

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics
por: Krieger, Teresa G, et al.
Publicado: (2020)

Author Correction: Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids
por: Fiorenzano, Alessandro, et al.
Publicado: (2022)

Single-cell transcriptomics of human-skin-equivalent organoids
por: Stabell, Adam R., et al.
Publicado: (2023)

Vascularized human cortical organoids (vOrganoids) model cortical development in vivo
por: Shi, Yingchao, et al.
Publicado: (2020)

Transcriptomic Profiling of Tetrodotoxin-Induced Neurotoxicity in Human Cerebral Organoids
por: Liu, Zhanbiao, et al.
Publicado: (2023)

Improved Retinal Organoid Differentiation by Modulating Signaling Pathways Revealed by Comparative Transcriptome Analyses with Development In Vivo
por: Brooks, Matthew J., et al.
Publicado: (2019)

BIOL-02. MODELING BRAIN TUMORS IN VIVO AND WITH HUMAN ORGANOIDS
por: Tiberi, Luca
Publicado: (2023)

Engineering cerebral folding in brain organoids
por: Scott, Glen, et al.
Publicado: (2022)

Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids
por: Sen, Dilara, et al.
Publicado: (2021)

Modeling human brain development with cerebral organoids
por: Muzio, Luca, et al.
Publicado: (2013)

Single Cell Transcriptomic Analyses Reveal the Impact of bHLH Factors on Human Retinal Organoid Development
por: Zhang, Xiangmei, et al.
Publicado: (2021)

Modeling Brain Tumors: A Perspective Overview of in vivo and Organoid Models
por: Antonica, Francesco, et al.
Publicado: (2022)

Engraftment of Kidney Organoids In Vivo
por: Freedman, Benjamin S., et al.
Publicado: (2023)

Mechanically induced development and maturation of human intestinal organoids in vivo
por: Poling, Holly M., et al.
Publicado: (2018)

Integration of Genomic Profiling and Organoid Development in Precision Oncology
por: Yoon, Hyunho, et al.
Publicado: (2021)

Vascularizing the brain organoids
por: Sun, Xin-Yao, et al.
Publicado: (2022)

Cerebral organoids model human brain development and microcephaly
por: Lancaster, Madeline A., et al.
Publicado: (2013)

Modeling the Human Brain With ex vivo Slices and in vitro Organoids for Translational Neuroscience
por: Nogueira, Giovanna O., et al.
Publicado: (2022)

High-throughput scNMT protocol for multiomics profiling of single cells from mouse brain and pancreatic organoids
por: Cerrizuela, Santiago, et al.
Publicado: (2022)

RNA-sequencing of single cholangiocyte-derived organoids reveals high organoid-to organoid variability
por: Gehling, Kristin, et al.
Publicado: (2022)

Brain Organoids: Studying Human Brain Development and Diseases in a Dish
por: Xu, Jie, et al.
Publicado: (2021)

Microglia-containing human brain organoids for the study of brain development and pathology
por: Zhang, Wendiao, et al.
Publicado: (2022)

Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling
por: Lu, Jing, et al.
Publicado: (2021)

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets
por: Vértesy, Ábel, et al.
Publicado: (2022)

Modelling of pancreatic cancer biology: transcriptomic signature for 3D PDX-derived organoids and primary cell line organoid development
por: Nelson, Shannon R., et al.
Publicado: (2020)

Single-cell brain organoid screening identifies developmental defects in autism
por: Li, Chong, et al.
Publicado: (2023)

Single-Cell Dynamic Analysis of Mitosis in Haploid Embryonic Stem Cells Shows the Prolonged Metaphase and Its Association with Self-diploidization
por: Guo, Ao, et al.
Publicado: (2017)

The Application of Brain Organoids: From Neuronal Development to Neurological Diseases
por: Shou, Yikai, et al.
Publicado: (2020)

Development of human brain organoids with functional vascular-like system
por: Cakir, Bilal, et al.
Publicado: (2019)

Unraveling Human Brain Development and Evolution Using Organoid Models
por: Fernandes, Sarah, et al.
Publicado: (2021)

Human Brain Organoids in Migraine Research: Pathogenesis and Drug Development
por: Gazerani, Parisa
Publicado: (2023)

Modeling human neurodevelopmental diseases with brain organoids
por: Lu, Xiaoxiang, et al.
Publicado: (2022)

Alzheimer’s Amyloid-β Accelerates Human Neuronal Cell Senescence Which Could Be Rescued by Sirtuin-1 and Aspirin
por: Li, Yi, et al.
Publicado: (2022)

Genetic Modification of Brain Organoids
por: Fischer, Jan, et al.
Publicado: (2019)

Brain organoids: Establishment and application
por: Chen, Hao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4a4d62ok81nbhg9kb97kb8uocu