Cargando…

Dysregulation of the Nitric Oxide/Dimethylarginine Pathway in Hypoxic Pulmonary Vasoconstriction—Molecular Mechanisms and Clinical Significance

The pulmonary circulation responds to hypoxia with vasoconstriction, a mechanism that helps to adapt to short-lived hypoxic episodes. When sustained, hypoxic pulmonary vasoconstriction (HPV) may become deleterious, causing right ventricular hypertrophy and failure, and contributing to morbidity and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hannemann, Juliane, Böger, Rainer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891573/ https://www.ncbi.nlm.nih.gov/pubmed/35252268 http://dx.doi.org/10.3389/fmed.2022.835481

Ejemplares similares

Dual role of the L-arginine–ADMA–NO pathway in systemic hypoxic vasodilation and pulmonary hypoxic vasoconstriction
por: Böger, Rainer, et al.
Publicado: (2020)

Biomarkers of the L-Arginine/Dimethylarginine/Nitric Oxide Pathway in People with Chronic Airflow Obstruction and Obstructive Sleep Apnoea
por: Hannemann, Juliane, et al.
Publicado: (2023)

Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude
por: Siques, Patricia, et al.
Publicado: (2019)

Metabolism of asymmetric dimethylarginine in hypoxia: from bench to bedside
por: Hannemann, Juliane, et al.
Publicado: (2020)

Association of Genes of the NO Pathway with Altitude Disease and Hypoxic Pulmonary Hypertension
por: Hannemann, Juliane, et al.
Publicado: (2021)

Hypoxic Pulmonary Vasoconstriction in Humans
por: Ariyaratnam, Priyadharshanan, et al.
Publicado: (2013)

Deciphering the molecular mechanisms of pulmonary hypoxia and its health sequelae: proceedings of the first international DECIPHER symposium on pulmonary hypoxia, Iquique, Chile, 16–17 October 2019
por: Hannemann, Juliane, et al.
Publicado: (2020)

Pre-Analytical and Clinical Validation of a Dried Blood Spot Assay for Asymmetric Dimethylarginine and L-Arginine
por: Hannemann, Juliane, et al.
Publicado: (2020)

Asymmetric dimethylarginine predicts perioperative cardiovascular complications in patients undergoing medium-to-high risk non-cardiac surgery
por: Appel, Daniel, et al.
Publicado: (2020)

Diurnal Variation of L-Arginine and the Cardiovascular Risk Markers Asymmetric and Symmetric Dimethylarginine and Homoarginine in Rotating Night Shift Workers and Controls
por: Hannemann, Juliane, et al.
Publicado: (2023)

Associations of circulating dimethylarginines with the metabolic syndrome in the Framingham Offspring study
por: Yola, Ibrahim Musa, et al.
Publicado: (2021)

Hypercapnic acidosis transiently weakens hypoxic pulmonary vasoconstriction in anesthetized pigs, without affecting the endogenous pulmonary nitric oxide production
por: Nilsson, MC, et al.
Publicado: (2011)

Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
por: Paddenberg, Renate, et al.
Publicado: (2014)

Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth
por: Hussain, A., et al.
Publicado: (2017)

Mitochondrial transplantation attenuates hypoxic pulmonary vasoconstriction
por: Zhou, Juan, et al.
Publicado: (2016)

Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?
por: Lüneburg, Nicole, et al.
Publicado: (2016)

Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults
por: Lüneburg, Nicole, et al.
Publicado: (2017)

Inhibition of Hypoxic Pulmonary Vasoconstriction of Rats by Carbon Monoxide
por: Yoo, Hae Young, et al.
Publicado: (2010)

Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia
por: Petersen, Bodil, et al.
Publicado: (2019)

Live and let die: asymmetric dimethylarginine and septic shock
por: Böger, Rainer H
Publicado: (2006)

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction
por: Cogolludo, Angel, et al.
Publicado: (2009)

Effects of hypercapnia and NO synthase inhibition in sustained hypoxic pulmonary vasoconstriction
por: Ketabchi, Farzaneh, et al.
Publicado: (2012)

Hypoxic pulmonary vasoconstriction: role of voltage-gated potassium channels
por: Sweeney, Michèle, et al.
Publicado: (2000)

Impairment of hypoxic pulmonary vasoconstriction in acute respiratory distress syndrome
por: Gierhardt, Mareike, et al.
Publicado: (2021)

The role of asymmetric dimethylarginine (ADMA) in COVID-19: association with respiratory failure and predictive role for outcome
por: Sozio, Emanuela, et al.
Publicado: (2023)

Nitric oxide inhibition sustains vasopressin-induced vasoconstriction.
por: Dworkin, M. J., et al.
Publicado: (1995)

Hypoxic pulmonary vasoconstriction in isolated rat pulmonary arteries is not inhibited by antagonists of H(2)S-synthesizing pathways
por: Prieto-Lloret, Jesus, et al.
Publicado: (2015)

Inhibition of nitric oxide synthase unmasks vigorous vasoconstriction in established pulmonary arterial hypertension
por: Tanaka, Mariko, et al.
Publicado: (2017)

Increased asymmetric dimethylarginine and nitric oxide levels in patients with migraine
por: Uzar, Ertugrul, et al.
Publicado: (2011)

Asymmetric Dimethylarginine, Endothelial Nitric Oxide Bioavailability and Mortality in Sepsis
por: Davis, Joshua S., et al.
Publicado: (2011)

Roles of Nitric Oxide and Asymmetric Dimethylarginine in Pregnancy and Fetal Programming
por: Huang, Li-Tung, et al.
Publicado: (2012)

Hypoxic Pulmonary Vasoconstriction and the Diffusing Capacity in Pulmonary Hypertension Secondary to Idiopathic Pulmonary Fibrosis
por: Sakao, Seiichiro, et al.
Publicado: (2019)

Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery
por: Knock, Greg A., et al.
Publicado: (2008)

Endogenous angiotensin II in the regulation of hypoxic pulmonary vasoconstriction in anaesthetized dogs
por: Hubloue, Ives, et al.
Publicado: (2004)

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6
por: Fuchs, Beate, et al.
Publicado: (2011)

Riociguat versus sildenafil on hypoxic pulmonary vasoconstriction and ventilation/perfusion matching
por: Chamorro, Virginia, et al.
Publicado: (2018)

Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
por: Turzo, Maurizio, et al.
Publicado: (2018)

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome
por: Schleifer, Grigorij, et al.
Publicado: (2019)

Inhibition of ornithine decarboxylase restores hypoxic pulmonary vasoconstriction in endotoxemic mice
por: Gebauer, P.H., et al.
Publicado: (2020)

The hypoxic pulmonary vasoconstriction: From physiology to clinical application in thoracic surgery
por: Licker, Marc, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f50pshq6p7qksc7jeqfulqpjgm