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Hearing Recovery Induced by DNA Demethylation in a Chemically Deafened Adult Mouse Model

Functional hair cell regeneration in the adult mammalian inner ear remains challenging. This study aimed to study the function of new hair cells induced by a DNA demethylating agent 5-azacytidine. Adult mice were deafened chemically, followed by injection of 5-azacytidine or vehicle into the inner e...

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Detalles Bibliográficos
Autores principales: Deng, Xin, Hu, Zhengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891629/
https://www.ncbi.nlm.nih.gov/pubmed/35250483
http://dx.doi.org/10.3389/fncel.2022.792089