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Bone mineral density in fracture neck of femur patients: What's the significance?

BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To in...

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Autores principales: Elamin Ahmed, Hussam, Al-Dadah, Oday
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891661/
https://www.ncbi.nlm.nih.gov/pubmed/35317402
http://dx.doi.org/10.5312/wjo.v13.i2.160
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author Elamin Ahmed, Hussam
Al-Dadah, Oday
author_facet Elamin Ahmed, Hussam
Al-Dadah, Oday
author_sort Elamin Ahmed, Hussam
collection PubMed
description BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To investigate the significance of BMD in fracture neck of femur patients and compare it to the outcome of the FRAX score. METHODS: Inclusion criteria for this study were all patients who underwent dual-energy X-ray absorptiometry (DXA) scan following fracture neck of femur between 2015 and 2017. Analysis of BMD, FRAX scores and patient demographic data was undertaken. RESULTS: A total of 69 patients were included in the study, mean age 74.1 years. There was no significant difference between mean BMD of the femoral neck in males (0.65) as compared to females (0.61) (P = 0.364). Analyses showed no significant correlation between BMD and menopause age (r(s )= -0.28, P = 0.090). A significant difference was seen of the femoral neck BMD between the different fracture pattern types (P = 0.026). A stronger correlation was observed between BMD of femoral neck and FRAX major score (r(s )= -0.64, P < 0.001) than with BMD of lumbar spine and FRAX major score (r(s )= -0.37, P = 0.003). CONCLUSION: This study demonstrated that BMD of the femoral neck measured by DXA scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system.
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spelling pubmed-88916612022-03-21 Bone mineral density in fracture neck of femur patients: What's the significance? Elamin Ahmed, Hussam Al-Dadah, Oday World J Orthop Observational Study BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To investigate the significance of BMD in fracture neck of femur patients and compare it to the outcome of the FRAX score. METHODS: Inclusion criteria for this study were all patients who underwent dual-energy X-ray absorptiometry (DXA) scan following fracture neck of femur between 2015 and 2017. Analysis of BMD, FRAX scores and patient demographic data was undertaken. RESULTS: A total of 69 patients were included in the study, mean age 74.1 years. There was no significant difference between mean BMD of the femoral neck in males (0.65) as compared to females (0.61) (P = 0.364). Analyses showed no significant correlation between BMD and menopause age (r(s )= -0.28, P = 0.090). A significant difference was seen of the femoral neck BMD between the different fracture pattern types (P = 0.026). A stronger correlation was observed between BMD of femoral neck and FRAX major score (r(s )= -0.64, P < 0.001) than with BMD of lumbar spine and FRAX major score (r(s )= -0.37, P = 0.003). CONCLUSION: This study demonstrated that BMD of the femoral neck measured by DXA scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system. Baishideng Publishing Group Inc 2022-02-18 /pmc/articles/PMC8891661/ /pubmed/35317402 http://dx.doi.org/10.5312/wjo.v13.i2.160 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Noncommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Observational Study
Elamin Ahmed, Hussam
Al-Dadah, Oday
Bone mineral density in fracture neck of femur patients: What's the significance?
title Bone mineral density in fracture neck of femur patients: What's the significance?
title_full Bone mineral density in fracture neck of femur patients: What's the significance?
title_fullStr Bone mineral density in fracture neck of femur patients: What's the significance?
title_full_unstemmed Bone mineral density in fracture neck of femur patients: What's the significance?
title_short Bone mineral density in fracture neck of femur patients: What's the significance?
title_sort bone mineral density in fracture neck of femur patients: what's the significance?
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891661/
https://www.ncbi.nlm.nih.gov/pubmed/35317402
http://dx.doi.org/10.5312/wjo.v13.i2.160
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