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Bone mineral density in fracture neck of femur patients: What's the significance?
BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To in...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891661/ https://www.ncbi.nlm.nih.gov/pubmed/35317402 http://dx.doi.org/10.5312/wjo.v13.i2.160 |
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author | Elamin Ahmed, Hussam Al-Dadah, Oday |
author_facet | Elamin Ahmed, Hussam Al-Dadah, Oday |
author_sort | Elamin Ahmed, Hussam |
collection | PubMed |
description | BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To investigate the significance of BMD in fracture neck of femur patients and compare it to the outcome of the FRAX score. METHODS: Inclusion criteria for this study were all patients who underwent dual-energy X-ray absorptiometry (DXA) scan following fracture neck of femur between 2015 and 2017. Analysis of BMD, FRAX scores and patient demographic data was undertaken. RESULTS: A total of 69 patients were included in the study, mean age 74.1 years. There was no significant difference between mean BMD of the femoral neck in males (0.65) as compared to females (0.61) (P = 0.364). Analyses showed no significant correlation between BMD and menopause age (r(s )= -0.28, P = 0.090). A significant difference was seen of the femoral neck BMD between the different fracture pattern types (P = 0.026). A stronger correlation was observed between BMD of femoral neck and FRAX major score (r(s )= -0.64, P < 0.001) than with BMD of lumbar spine and FRAX major score (r(s )= -0.37, P = 0.003). CONCLUSION: This study demonstrated that BMD of the femoral neck measured by DXA scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system. |
format | Online Article Text |
id | pubmed-8891661 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-88916612022-03-21 Bone mineral density in fracture neck of femur patients: What's the significance? Elamin Ahmed, Hussam Al-Dadah, Oday World J Orthop Observational Study BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines have advised further research is required into investigating the added prognostic value of bone mineral density (BMD) in the assessment of fracture risk with the Fracture Risk Assessment Tool (FRAX) score. AIM: To investigate the significance of BMD in fracture neck of femur patients and compare it to the outcome of the FRAX score. METHODS: Inclusion criteria for this study were all patients who underwent dual-energy X-ray absorptiometry (DXA) scan following fracture neck of femur between 2015 and 2017. Analysis of BMD, FRAX scores and patient demographic data was undertaken. RESULTS: A total of 69 patients were included in the study, mean age 74.1 years. There was no significant difference between mean BMD of the femoral neck in males (0.65) as compared to females (0.61) (P = 0.364). Analyses showed no significant correlation between BMD and menopause age (r(s )= -0.28, P = 0.090). A significant difference was seen of the femoral neck BMD between the different fracture pattern types (P = 0.026). A stronger correlation was observed between BMD of femoral neck and FRAX major score (r(s )= -0.64, P < 0.001) than with BMD of lumbar spine and FRAX major score (r(s )= -0.37, P = 0.003). CONCLUSION: This study demonstrated that BMD of the femoral neck measured by DXA scan is of added prognostic value when assessing patients for risk of fracture neck of femur in combination with the FRAX predictive scoring system. Baishideng Publishing Group Inc 2022-02-18 /pmc/articles/PMC8891661/ /pubmed/35317402 http://dx.doi.org/10.5312/wjo.v13.i2.160 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Noncommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Observational Study Elamin Ahmed, Hussam Al-Dadah, Oday Bone mineral density in fracture neck of femur patients: What's the significance? |
title | Bone mineral density in fracture neck of femur patients: What's the significance? |
title_full | Bone mineral density in fracture neck of femur patients: What's the significance? |
title_fullStr | Bone mineral density in fracture neck of femur patients: What's the significance? |
title_full_unstemmed | Bone mineral density in fracture neck of femur patients: What's the significance? |
title_short | Bone mineral density in fracture neck of femur patients: What's the significance? |
title_sort | bone mineral density in fracture neck of femur patients: what's the significance? |
topic | Observational Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891661/ https://www.ncbi.nlm.nih.gov/pubmed/35317402 http://dx.doi.org/10.5312/wjo.v13.i2.160 |
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