Step-up approach in emphysematous hepatitis: A case report

BACKGROUND: Emphysematous hepatitis (EH) is a rare, rapidly progressive fulminant gas-forming infection of the liver parenchyma. It is often fatal and mostly affects diabetes patients. CASE SUMMARY: We report a case of EH successfully managed by a step-up approach consisting of aggressive hemodynami...

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Autores principales: Francois, Silke, Aerts, Maridi, Reynaert, Hendrik, Van Lancker, Ruth, Van Laethem, Johan, Kunda, Rastislav, Messaoudi, Nouredin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891666/
https://www.ncbi.nlm.nih.gov/pubmed/35317184
http://dx.doi.org/10.4254/wjh.v14.i2.464
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author Francois, Silke
Aerts, Maridi
Reynaert, Hendrik
Van Lancker, Ruth
Van Laethem, Johan
Kunda, Rastislav
Messaoudi, Nouredin
author_facet Francois, Silke
Aerts, Maridi
Reynaert, Hendrik
Van Lancker, Ruth
Van Laethem, Johan
Kunda, Rastislav
Messaoudi, Nouredin
author_sort Francois, Silke
collection PubMed
description BACKGROUND: Emphysematous hepatitis (EH) is a rare, rapidly progressive fulminant gas-forming infection of the liver parenchyma. It is often fatal and mostly affects diabetes patients. CASE SUMMARY: We report a case of EH successfully managed by a step-up approach consisting of aggressive hemodynamic support, intravenous antibiotics, and percutaneous drainage, ultimately followed by laparoscopic deroofing. Of 11 documented cases worldwide, only 1 of the patients survived, treated by urgent laparotomy and surgical debridement. CONCLUSION: EH is a life-threatening infection. Its high mortality rate makes timely diagnosis essential, in order to navigate treatment accordingly.
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spelling pubmed-88916662022-03-21 Step-up approach in emphysematous hepatitis: A case report Francois, Silke Aerts, Maridi Reynaert, Hendrik Van Lancker, Ruth Van Laethem, Johan Kunda, Rastislav Messaoudi, Nouredin World J Hepatol Case Report BACKGROUND: Emphysematous hepatitis (EH) is a rare, rapidly progressive fulminant gas-forming infection of the liver parenchyma. It is often fatal and mostly affects diabetes patients. CASE SUMMARY: We report a case of EH successfully managed by a step-up approach consisting of aggressive hemodynamic support, intravenous antibiotics, and percutaneous drainage, ultimately followed by laparoscopic deroofing. Of 11 documented cases worldwide, only 1 of the patients survived, treated by urgent laparotomy and surgical debridement. CONCLUSION: EH is a life-threatening infection. Its high mortality rate makes timely diagnosis essential, in order to navigate treatment accordingly. Baishideng Publishing Group Inc 2022-02-27 2022-02-27 /pmc/articles/PMC8891666/ /pubmed/35317184 http://dx.doi.org/10.4254/wjh.v14.i2.464 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Francois, Silke
Aerts, Maridi
Reynaert, Hendrik
Van Lancker, Ruth
Van Laethem, Johan
Kunda, Rastislav
Messaoudi, Nouredin
Step-up approach in emphysematous hepatitis: A case report
title Step-up approach in emphysematous hepatitis: A case report
title_full Step-up approach in emphysematous hepatitis: A case report
title_fullStr Step-up approach in emphysematous hepatitis: A case report
title_full_unstemmed Step-up approach in emphysematous hepatitis: A case report
title_short Step-up approach in emphysematous hepatitis: A case report
title_sort step-up approach in emphysematous hepatitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891666/
https://www.ncbi.nlm.nih.gov/pubmed/35317184
http://dx.doi.org/10.4254/wjh.v14.i2.464
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