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Macrophage MerTK promotes profibrogenic cross-talk with hepatic stellate cells via soluble mediators

BACKGROUND & AIMS: Activation of Kupffer cells and recruitment of monocytes are key events in fibrogenesis. These cells release soluble mediators which induce the activation of hepatic stellate cells (HSCs), the main fibrogenic cell type within the liver. Mer tyrosine kinase (MerTK) signaling re...

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Detalles Bibliográficos
Autores principales:	Pastore, Mirella, Caligiuri, Alessandra, Raggi, Chiara, Navari, Nadia, Piombanti, Benedetta, Di Maira, Giovanni, Rovida, Elisabetta, Piccinni, Marie-Pierre, Lombardelli, Letizia, Logiodice, Federica, Rombouts, Krista, Petta, Salvatore, Marra, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891698/ https://www.ncbi.nlm.nih.gov/pubmed/35252828 http://dx.doi.org/10.1016/j.jhepr.2022.100444

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