Cargando…

Decoding Human Genome Regulatory Features That Influence HIV-1 Proviral Expression and Fate Through an Integrated Genomics Approach

Fundamental principles of HIV-1 integration into the human genome have been revealed in the past 2 decades. However, the impact of the integration site on proviral transcription and expression remains poorly understood. Solving this problem requires the analysis of multiple genomic datasets for thou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruess, Holly, Lee, Jeon, Guzman, Carlos, Malladi, Venkat S, D’Orso, Iván
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891870/ https://www.ncbi.nlm.nih.gov/pubmed/35250265 http://dx.doi.org/10.1177/11779322211072333

Ejemplares similares

HIV-1 Proviral Transcription and Latency in the New Era
por: Shukla, Ashutosh, et al.
Publicado: (2020)

CIPHER: a flexible and extensive workflow platform for integrative next-generation sequencing data analysis and genomic regulatory element prediction
por: Guzman, Carlos, et al.
Publicado: (2017)

Damaging the Integrated HIV Proviral DNA with TALENs
por: Strong, Christy L., et al.
Publicado: (2015)

Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II
por: McNamara, Ryan P., et al.
Publicado: (2016)

Decoding the genome with an integrative analysis tool: Combinatorial CRM Decoder
por: Kang, Keunsoo, et al.
Publicado: (2011)

Mathematical Models of HIV-1 Dynamics, Transcription, and Latency
por: D’Orso, Iván, et al.
Publicado: (2023)

HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear
por: D’Orso, Iván, et al.
Publicado: (2010)

HTLV-1 Integration into Transcriptionally Active Genomic Regions Is Associated with Proviral Expression and with HAM/TSP
por: Meekings, Kiran N., et al.
Publicado: (2008)

Improving the methodology for the detection of proviral integration sites in the host genome via high throughput sequencing
por: Durkin, Keith, et al.
Publicado: (2015)

Crystal structure of an engineered, HIV-specific recombinase for removal of integrated proviral DNA
por: Meinke, Gretchen, et al.
Publicado: (2017)

HIV proviral DNA integration can drive T cell growth ex vivo
por: Yoon, John K., et al.
Publicado: (2020)

Structure and possible function of a G-quadruplex in the long terminal repeat of the proviral HIV-1 genome
por: De Nicola, Beatrice, et al.
Publicado: (2016)

Specific Destruction of HIV Proviral p17 Gene in T Lymphoid Cells Achieved by the Genome Editing Technology
por: Kishida, Tsunao, et al.
Publicado: (2016)

Proviral HIV-genome-wide and pol-gene specific Zinc Finger Nucleases: Usability for targeted HIV gene therapy
por: Wayengera, Misaki
Publicado: (2011)

Decoding a highly mixed Kazakh genome
por: Seidualy, Madina, et al.
Publicado: (2020)

A point mutation in HIV-1 integrase redirects proviral integration into centromeric repeats
por: Winans, Shelby, et al.
Publicado: (2022)

Variation in proviral content among human genomes mediated by LTR recombination
por: Thomas, Jainy, et al.
Publicado: (2018)

Identification and characterization of a novel enhancer in the HTLV-1 proviral genome
por: Matsuo, Misaki, et al.
Publicado: (2022)

Decoding the human genome
por: Frazer, Kelly A.
Publicado: (2012)

Decoding the human genome
por: Mauron, Alexandre, et al.
Publicado: (2002)

Bioinformatics: decoding the genome
por: Jongeneel, C Victor, et al.
Publicado: (2006)

Decoding poxvirus genome
por: Yang, Zhilong, et al.
Publicado: (2015)

An integrative method to decode regulatory logics in gene transcription
por: Yan, Bin, et al.
Publicado: (2017)

Chemistry and Bioinformatics Considerations in Using Next-Generation Sequencing Technologies to Inferring HIV Proviral DNA Genome-Intactness
por: Lee, Guinevere Q.
Publicado: (2021)

Integrative functional genomics decodes herpes simplex virus 1
por: Whisnant, Adam W., et al.
Publicado: (2020)

Expression Level of HIV-1 Vif Can Be Fluctuated by Natural Nucleotide Variations in the vif-Coding and Regulatory SA1D2prox Sequences of the Proviral Genome
por: Doi, Naoya, et al.
Publicado: (2019)

HIV-PULSE: a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterization
por: Lambrechts, Laurens, et al.
Publicado: (2023)

A9 A method to obtain full-length HIV proviral sequences and their sites of integration
por: Patro, Sean C, et al.
Publicado: (2019)

Ribosome Fate during Decoding of UGA-Sec Codons
por: Copeland, Paul R., et al.
Publicado: (2021)

Near-Complete Proviral Genome Sequence of Reticuloendotheliosis Virus Isolated from an Attwater’s Prairie Chicken (Tympanuchus cupido attwateri)
por: Willis, Bianca, et al.
Publicado: (2022)

NanoHIV: A Bioinformatics Pipeline for Producing Accurate, Near Full-Length HIV Proviral Genomes Sequenced Using the Oxford Nanopore Technology
por: Wright, Imogen A., et al.
Publicado: (2021)

Epigenetic modifications of HIV proviral LTRs: potential targets for cure
por: Doerfler, W, et al.
Publicado: (2012)

Differential proviral latency of the HIV-1 subtypes B and AE
por: van der Sluis, Renée M, et al.
Publicado: (2011)

HIV‐1 proviral landscape characterization varies by pipeline analysis
por: Ferreira, Fernanda A, et al.
Publicado: (2021)

i-cisTarget: an integrative genomics method for the prediction of regulatory features and cis-regulatory modules
por: Herrmann, Carl, et al.
Publicado: (2012)

Genetic Characterization of HIV-1 Subtype D Near-Full-Length Proviral Genomes by Illumina Massively Parallel Sequencing Technology
por: Pessôa, Rodrigo, et al.
Publicado: (2014)

Mamo decodes hierarchical temporal gradients into terminal neuronal fate
por: Liu, Ling-Yu, et al.
Publicado: (2019)

Transcriptional features of genomic regulatory blocks
por: Akalin, Altuna, et al.
Publicado: (2009)

The Blast Fungus Decoded: Genomes in Flux
por: Langner, Thorsten, et al.
Publicado: (2018)

Feasibility of testing and detection of HIV-1 drug resistance in proviral DNA
por: Booth, Clare L, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7lm4angarcultcmcpq7m685oj0