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Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues

Quantification of scattered photons in addition to unscattered primary particles, under realistic exposure scenario, is best dealt with a parameter called “Buildup factor”. The aim of this work is to simulate the transmission buildup factor (BUF) of gamma-ray in the energy range .15–15 MeV for 20 hu...

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Autores principales: Alfuraih, Abdulrahman A., Kadri, Omrane M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891879/
https://www.ncbi.nlm.nih.gov/pubmed/35250407
http://dx.doi.org/10.1177/15593258211068621
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author Alfuraih, Abdulrahman A.
Kadri, Omrane M.
author_facet Alfuraih, Abdulrahman A.
Kadri, Omrane M.
author_sort Alfuraih, Abdulrahman A.
collection PubMed
description Quantification of scattered photons in addition to unscattered primary particles, under realistic exposure scenario, is best dealt with a parameter called “Buildup factor”. The aim of this work is to simulate the transmission buildup factor (BUF) of gamma-ray in the energy range .15–15 MeV for 20 human tissues and organs using the Geant4 (version 10.5) Monte Carlo simulation followed by a geometrical progression (GP) parameterization procedure. Firstly, we verified the accuracy of Geant4 ability to predict the effective transmitted dose according to published data. Also, a comparison of simulated BUF for different geometrical configurations was carried out for some tissues and source energies. Then, we checked out the linear dependency of the K parameter (BUF is function of K) function of mean free path (mfp). Finally, we developed a fitting procedure according to GP method for BUF corresponding to 20 tissues and organs and different mfp (from 1 to 8) for energy range .15–15 MeV. We found a good agreement with previous published data. Proper comprehension of BUF for tissues leads to carefully controlling the energy absorption in the human body. Consequently, provided BUF could be of great interest for estimating safe dose levels in medical imaging and radiation therapy.
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spelling pubmed-88918792022-03-04 Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues Alfuraih, Abdulrahman A. Kadri, Omrane M. Dose Response Original Article Quantification of scattered photons in addition to unscattered primary particles, under realistic exposure scenario, is best dealt with a parameter called “Buildup factor”. The aim of this work is to simulate the transmission buildup factor (BUF) of gamma-ray in the energy range .15–15 MeV for 20 human tissues and organs using the Geant4 (version 10.5) Monte Carlo simulation followed by a geometrical progression (GP) parameterization procedure. Firstly, we verified the accuracy of Geant4 ability to predict the effective transmitted dose according to published data. Also, a comparison of simulated BUF for different geometrical configurations was carried out for some tissues and source energies. Then, we checked out the linear dependency of the K parameter (BUF is function of K) function of mean free path (mfp). Finally, we developed a fitting procedure according to GP method for BUF corresponding to 20 tissues and organs and different mfp (from 1 to 8) for energy range .15–15 MeV. We found a good agreement with previous published data. Proper comprehension of BUF for tissues leads to carefully controlling the energy absorption in the human body. Consequently, provided BUF could be of great interest for estimating safe dose levels in medical imaging and radiation therapy. SAGE Publications 2022-03-01 /pmc/articles/PMC8891879/ /pubmed/35250407 http://dx.doi.org/10.1177/15593258211068621 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Alfuraih, Abdulrahman A.
Kadri, Omrane M.
Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title_full Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title_fullStr Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title_full_unstemmed Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title_short Geant4 Simulation of Gamma-Ray Transmission Buildup Factors for Human Tissues
title_sort geant4 simulation of gamma-ray transmission buildup factors for human tissues
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891879/
https://www.ncbi.nlm.nih.gov/pubmed/35250407
http://dx.doi.org/10.1177/15593258211068621
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