Regulatory domains controlling high intestinal vitamin D receptor gene expression are conserved in mouse and human

Vitamin D receptor (VDR) levels are highest in the intestine where it mediates 1,25 dihydroxyvitamin D-induced gene expression. However, the mechanisms controlling high intestinal VDR gene expression are unknown. Here, we used Assay for Transposase-Accessible Chromatin using Sequencing (ATAC-Seq) to...

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Detalles Bibliográficos
Autores principales: Fleet, James C., Aldea, Dennis, Chen, Lei, Christakos, Sylvia, Verzi, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891975/
https://www.ncbi.nlm.nih.gov/pubmed/35065959
http://dx.doi.org/10.1016/j.jbc.2022.101616

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