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Inflammasome regulation by adaptor isoforms, ASC and ASCb, via differential self-assembly

ASC is an essential adaptor of the inflammasome, a micrometer-size multiprotein complex that processes proinflammatory cytokines. Inflammasome formation depends on ASC self-association into large assemblies via homotypic interactions of its two death domains, PYD and CARD. ASCb, an alternative splic...

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Detalles Bibliográficos
Autores principales:	Diaz-Parga, Pedro, de Alba, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8891976/ https://www.ncbi.nlm.nih.gov/pubmed/35007535 http://dx.doi.org/10.1016/j.jbc.2022.101566

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