Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6

Human AlkB homolog 6, ALKBH6, plays key roles in nucleic acid damage repair and tumor therapy. However, no precise structural and functional information are available for this protein. In this study, we determined atomic resolution crystal structures of human holo-ALKBH6 and its complex with ligands...

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Detalles Bibliográficos
Autores principales: Ma, Lulu, Lu, Hongyun, Tian, Zizi, Yang, Meiting, Ma, Jun, Shang, Guohui, Liu, Yunlong, Xie, Mengjia, Wang, Guoguo, Wu, Wei, Zhang, Ziding, Dai, Shaodong, Chen, Zhongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892091/
https://www.ncbi.nlm.nih.gov/pubmed/35120926
http://dx.doi.org/10.1016/j.jbc.2022.101671

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