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ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism

miRNAs are short noncoding RNA molecules that regulate gene expression by inhibiting translation or inducing degradation of target mRNAs. miRNAs are often expressed as polycistronic transcripts, so-called miRNA clusters, containing several miRNA precursors. The largest mammalian miRNA cluster, the m...

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Detalles Bibliográficos
Autores principales: Widmark, Albin, Sagredo, Eduardo A., Karlström, Victor, Behm, Mikaela, Biryukova, Inna, Friedländer, Marc R., Daniel, Chammiran, Öhman, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892144/
https://www.ncbi.nlm.nih.gov/pubmed/35124003
http://dx.doi.org/10.1016/j.jbc.2022.101682