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A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies

BACKGROUND: That Epstein–Barr virus (EBV) infection is associated with systemic lupus erythematosus (SLE) is established. The challenge is to explain mechanistic roles EBV has in SLE pathogenesis. Previous studies identify four examples of autoantibody cross-reactions between SLE autoantigens and Ep...

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Detalles Bibliográficos
Autores principales: Laurynenka, Viktoryia, Ding, Lili, Kaufman, Kenneth M., James, Judith A., Harley, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892314/
https://www.ncbi.nlm.nih.gov/pubmed/35251022
http://dx.doi.org/10.3389/fimmu.2022.830993

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