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The nonredundant nature of the Axin2 regulatory network in the canonical Wnt signaling pathway
Axin is one of two essential scaffolds in the canonical Wnt pathway that converts signals at the plasma membrane to signals inhibiting the degradation of β-catenin, leading to its accumulation and specific gene activation. In vertebrates, there are two forms of Axin, Axin1 and Axin2, which are simil...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892335/ https://www.ncbi.nlm.nih.gov/pubmed/35197279 http://dx.doi.org/10.1073/pnas.2108408119 |