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Ratiometric pH-Responsive (19)F Magnetic Resonance Imaging Contrast Agents Based on Hydrazone Switches

[Image: see text] Hydrazone-based molecular switches serve as efficient ratiometric pH-sensitive agents that can be tracked with (19)F NMR/MRI and (1)H NMR. Structural changes induced between pH 3 and 4 lead to signal appearance and disappearance at (1)H and (19)F NMR spectra allowing ratiometric pH...

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Detalles Bibliográficos
Autores principales: Janasik, Dawid, Jasiński, Krzysztof, Węglarz, Władysław P., Nemec, Ivan, Jewula, Pawel, Krawczyk, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892427/
https://www.ncbi.nlm.nih.gov/pubmed/35156816
http://dx.doi.org/10.1021/acs.analchem.1c04978