Cargando…
Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India
BACKGROUND: Primary data on causes and costs of hospitalization are necessary for costing and cost-effectiveness analysis. Data on incidence and causes of hospitalization and consequent expenses among Indian children are limited. METHODS: A cohort of 6000 children aged 0.5–15 years residing in urban...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892546/ https://www.ncbi.nlm.nih.gov/pubmed/35238368 http://dx.doi.org/10.1093/infdis/jiab329 |
_version_ | 1784662201708052480 |
---|---|
author | Srinivasan, Manikandan Sindhu, Kulandaipalayam Natarajan Nag, Atrayee Karthikeyan, Arun S Ramasamy, Ranjith Kumar Murugesan, Malathi Kumar, Dilesh Ganesan, Santhosh Kumar Rose, Winsley Kang, Gagandeep John, Jacob |
author_facet | Srinivasan, Manikandan Sindhu, Kulandaipalayam Natarajan Nag, Atrayee Karthikeyan, Arun S Ramasamy, Ranjith Kumar Murugesan, Malathi Kumar, Dilesh Ganesan, Santhosh Kumar Rose, Winsley Kang, Gagandeep John, Jacob |
author_sort | Srinivasan, Manikandan |
collection | PubMed |
description | BACKGROUND: Primary data on causes and costs of hospitalization are necessary for costing and cost-effectiveness analysis. Data on incidence and causes of hospitalization and consequent expenses among Indian children are limited. METHODS: A cohort of 6000 children aged 0.5–15 years residing in urban Vellore was followed for 3 years, under the Vellore Typhoid Study, 2016–2017, and later under the Surveillance for Enteric Fever project, 2017–2019. Data on hospitalization events and associated antibiotic use, and direct medical costs for fever-related hospitalization of study children were obtained from caregivers through weekly follow-up by study field workers. RESULTS: The incidence of hospitalization was 33 per 1000 child-years of observation. Children aged 0.5–5 years had the highest incidence of hospitalization. The top 5 infectious causes for hospitalization were acute undifferentiated fevers, respiratory tract infections, acute gastroenteritis, enteric fever, and dengue. The overall median cost of hospitalization for fever was 4243 (interquartile range, 2502–7215) Indian rupees (INR). An episode of dengue had a median cost of 5627 INR, followed by acute undifferentiated fevers and enteric fever with median costs of 3860 and 3507 INR, respectively. CONCLUSIONS: Hospitalization for fever is common in young children and impacts household finances in low-income Indian households. |
format | Online Article Text |
id | pubmed-8892546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-88925462022-03-04 Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India Srinivasan, Manikandan Sindhu, Kulandaipalayam Natarajan Nag, Atrayee Karthikeyan, Arun S Ramasamy, Ranjith Kumar Murugesan, Malathi Kumar, Dilesh Ganesan, Santhosh Kumar Rose, Winsley Kang, Gagandeep John, Jacob J Infect Dis Supplement Articles BACKGROUND: Primary data on causes and costs of hospitalization are necessary for costing and cost-effectiveness analysis. Data on incidence and causes of hospitalization and consequent expenses among Indian children are limited. METHODS: A cohort of 6000 children aged 0.5–15 years residing in urban Vellore was followed for 3 years, under the Vellore Typhoid Study, 2016–2017, and later under the Surveillance for Enteric Fever project, 2017–2019. Data on hospitalization events and associated antibiotic use, and direct medical costs for fever-related hospitalization of study children were obtained from caregivers through weekly follow-up by study field workers. RESULTS: The incidence of hospitalization was 33 per 1000 child-years of observation. Children aged 0.5–5 years had the highest incidence of hospitalization. The top 5 infectious causes for hospitalization were acute undifferentiated fevers, respiratory tract infections, acute gastroenteritis, enteric fever, and dengue. The overall median cost of hospitalization for fever was 4243 (interquartile range, 2502–7215) Indian rupees (INR). An episode of dengue had a median cost of 5627 INR, followed by acute undifferentiated fevers and enteric fever with median costs of 3860 and 3507 INR, respectively. CONCLUSIONS: Hospitalization for fever is common in young children and impacts household finances in low-income Indian households. Oxford University Press 2021-11-23 /pmc/articles/PMC8892546/ /pubmed/35238368 http://dx.doi.org/10.1093/infdis/jiab329 Text en © The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Supplement Articles Srinivasan, Manikandan Sindhu, Kulandaipalayam Natarajan Nag, Atrayee Karthikeyan, Arun S Ramasamy, Ranjith Kumar Murugesan, Malathi Kumar, Dilesh Ganesan, Santhosh Kumar Rose, Winsley Kang, Gagandeep John, Jacob Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title | Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title_full | Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title_fullStr | Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title_full_unstemmed | Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title_short | Hospitalization Rates and Direct Medical Costs for Fever in a Pediatric Cohort in South India |
title_sort | hospitalization rates and direct medical costs for fever in a pediatric cohort in south india |
topic | Supplement Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892546/ https://www.ncbi.nlm.nih.gov/pubmed/35238368 http://dx.doi.org/10.1093/infdis/jiab329 |
work_keys_str_mv | AT srinivasanmanikandan hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT sindhukulandaipalayamnatarajan hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT nagatrayee hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT karthikeyanaruns hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT ramasamyranjithkumar hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT murugesanmalathi hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT kumardilesh hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT ganesansanthoshkumar hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT rosewinsley hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT kanggagandeep hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia AT johnjacob hospitalizationratesanddirectmedicalcostsforfeverinapediatriccohortinsouthindia |