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Targeted Deletion of Centrin in Leishmania braziliensis Using CRISPR-Cas9-Based Editing

Leishmania braziliensis is the main causative agent of Tegumentary Leishmaniasis in the Americas. However, difficulties related to genome manipulation, experimental infection, and parasite growth have so far limited studies with this species. CRISPR-Cas9-based technology has made genome editing more...

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Detalles Bibliográficos
Autores principales:	Sharma, Rohit, Avendaño Rangel, Francys, Reis-Cunha, João Luís, Marques, Larissa Pinheiro, Figueira, Claudio P., Borba, Pedro B., Viana, Sayonara M., Beneke, Tom, Bartholomeu, Daniella C., de Oliveira, Camila I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892584/ https://www.ncbi.nlm.nih.gov/pubmed/35252020 http://dx.doi.org/10.3389/fcimb.2021.790418

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