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Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells

The Warburg effect or aerobic glycolysis is a hallmark of cancer. Lactate dehydrogenase (LDH), which catalyzes conversion of pyruvate into lactate, serves a critical role during Warburg effect. LDH A chain (LDHA), a member of the LDH family, is upregulated in multiple types of cancer and serves a vi...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenjing, Wang, Cui, Hu, Xiaomei, Lian, Yanzhen, Ding, Caili, Ming, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892607/ https://www.ncbi.nlm.nih.gov/pubmed/35191522 http://dx.doi.org/10.3892/or.2022.8288

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