Enhanced protein isoform characterization through long-read proteogenomics

BACKGROUND: The detection of physiologically relevant protein isoforms encoded by the human genome is critical to biomedicine. Mass spectrometry (MS)-based proteomics is the preeminent method for protein detection, but isoform-resolved proteomic analysis relies on accurate reference databases that m...

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Detalles Bibliográficos
Autores principales: Miller, Rachel M., Jordan, Ben T., Mehlferber, Madison M., Jeffery, Erin D., Chatzipantsiou, Christina, Kaur, Simi, Millikin, Robert J., Dai, Yunxiang, Tiberi, Simone, Castaldi, Peter J., Shortreed, Michael R., Luckey, Chance John, Conesa, Ana, Smith, Lloyd M., Deslattes Mays, Anne, Sheynkman, Gloria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892804/
https://www.ncbi.nlm.nih.gov/pubmed/35241129
http://dx.doi.org/10.1186/s13059-022-02624-y

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