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Meiosis-specific cohesin complexes display essential and distinct roles in mitotic embryonic stem cell chromosomes

BACKGROUND: Cohesin is a chromosome-associated SMC–kleisin complex that mediates sister chromatid cohesion, recombination, and most chromosomal processes during mitosis and meiosis. However, it remains unclear whether meiosis-specific cohesin complexes are functionally active in mitotic chromosomes....

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Detalles Bibliográficos
Autores principales: Choi, Eui-Hwan, Yoon, Seobin, Koh, Young Eun, Hong, Tae Kyung, Do, Jeong Tae, Lee, Bum-Kyu, Hahn, Yoonsoo, Kim, Keun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892811/
https://www.ncbi.nlm.nih.gov/pubmed/35241136
http://dx.doi.org/10.1186/s13059-022-02632-y