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Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature

BACKGROUND: Ever since the administration of early doses of COVID-19 vaccines, instances of adverse effects have been reported. Viral infections, specifically herpes simplex reinfection and coinfections, have been reported following administration of different types of vaccines. To our knowledge, th...

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Autores principales: Moslemi, Mohammadreza, Ardalan, Mohammadreza, Haramshahi, Morteza, Mirzaei, Homa, Sani, Sahba Khosousi, Dastgir, Ramtin, Dastgir, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892827/
https://www.ncbi.nlm.nih.gov/pubmed/35241013
http://dx.doi.org/10.1186/s12879-022-07186-9
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author Moslemi, Mohammadreza
Ardalan, Mohammadreza
Haramshahi, Morteza
Mirzaei, Homa
Sani, Sahba Khosousi
Dastgir, Ramtin
Dastgir, Nima
author_facet Moslemi, Mohammadreza
Ardalan, Mohammadreza
Haramshahi, Morteza
Mirzaei, Homa
Sani, Sahba Khosousi
Dastgir, Ramtin
Dastgir, Nima
author_sort Moslemi, Mohammadreza
collection PubMed
description BACKGROUND: Ever since the administration of early doses of COVID-19 vaccines, instances of adverse effects have been reported. Viral infections, specifically herpes simplex reinfection and coinfections, have been reported following administration of different types of vaccines. To our knowledge, there have not been any reports of herpes simplex encephalitis following administration of any type of COVID-19 vaccine to date. CASE PRESENTATION: In this article intends to report a case of herpes simplex encephalitis in a 27-year-old male patient who was vaccinated with the ChAdOx1 nCoV-19 vaccine. CONCLUSIONS: Our study suggests a possible but very rare side effect of ChAdOx1 nCoV-19 vaccine, which requires immediate medical attention and can lead to devastating consequences if left undiagnosed and untreated.
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spelling pubmed-88928272022-03-04 Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature Moslemi, Mohammadreza Ardalan, Mohammadreza Haramshahi, Morteza Mirzaei, Homa Sani, Sahba Khosousi Dastgir, Ramtin Dastgir, Nima BMC Infect Dis Case Report BACKGROUND: Ever since the administration of early doses of COVID-19 vaccines, instances of adverse effects have been reported. Viral infections, specifically herpes simplex reinfection and coinfections, have been reported following administration of different types of vaccines. To our knowledge, there have not been any reports of herpes simplex encephalitis following administration of any type of COVID-19 vaccine to date. CASE PRESENTATION: In this article intends to report a case of herpes simplex encephalitis in a 27-year-old male patient who was vaccinated with the ChAdOx1 nCoV-19 vaccine. CONCLUSIONS: Our study suggests a possible but very rare side effect of ChAdOx1 nCoV-19 vaccine, which requires immediate medical attention and can lead to devastating consequences if left undiagnosed and untreated. BioMed Central 2022-03-03 /pmc/articles/PMC8892827/ /pubmed/35241013 http://dx.doi.org/10.1186/s12879-022-07186-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Moslemi, Mohammadreza
Ardalan, Mohammadreza
Haramshahi, Morteza
Mirzaei, Homa
Sani, Sahba Khosousi
Dastgir, Ramtin
Dastgir, Nima
Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title_full Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title_fullStr Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title_full_unstemmed Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title_short Herpes simplex encephalitis following ChAdOx1 nCoV-19 vaccination: a case report and review of the literature
title_sort herpes simplex encephalitis following chadox1 ncov-19 vaccination: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892827/
https://www.ncbi.nlm.nih.gov/pubmed/35241013
http://dx.doi.org/10.1186/s12879-022-07186-9
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