Model Predictive Control with Integrated Model Reduction for a Continuous Lactide Ring-Opening Polymerization Process

[Image: see text] Poly(lactic acid) production has received increasing attention, mainly due to its inherent biodegradable thermoplastic properties and to its renewable-resource-based composition. This process is affected by changes in the operating conditions and by raw material impurities which influence the reaction rate and degrade the polymer properties. As the system model is multivariable with coupled dynamics and constraints, linear model predictive control (LMPC) is employed here. A model reduction technique is proposed to obtain an approximate linear representation of the nonlinear system around the operating point to minimize the calculation cost of the controller. The proposed LMPC approach is validated by simulation and is compared to a proportional-integral controller and a nonlinear model predictive control. It is found that LMPC has a superior performance in terms of off-spec time when a disturbance occurs in the feed, and it can restore the target conditions better and faster.