Chimeric RNA: DNA TracrRNA Improves Homology-Directed Repair In Vitro and In Vivo

Nearly 90% of human pathogenic mutations are caused by small genetic variations, and methods to correct these errors efficiently are critically important. One way to make small DNA changes is providing a single-stranded oligo deoxynucleotide (ssODN) containing an alteration coupled with a targeted d...

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Detalles Bibliográficos
Autores principales: Simone, Brandon W., Lee, Han B., Daby, Camden L., Ata, Hirotaka, Restrepo-Castillo, Santiago, Martínez-Gálvez, Gabriel, Kar, Bibekananda, Gendron, William A.C., Clark, Karl J., Ekker, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892967/
https://www.ncbi.nlm.nih.gov/pubmed/34935462
http://dx.doi.org/10.1089/crispr.2021.0087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892967/
https://www.ncbi.nlm.nih.gov/pubmed/34935462
http://dx.doi.org/10.1089/crispr.2021.0087

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