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Chimeric RNA: DNA TracrRNA Improves Homology-Directed Repair In Vitro and In Vivo
Nearly 90% of human pathogenic mutations are caused by small genetic variations, and methods to correct these errors efficiently are critically important. One way to make small DNA changes is providing a single-stranded oligo deoxynucleotide (ssODN) containing an alteration coupled with a targeted d...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892967/ https://www.ncbi.nlm.nih.gov/pubmed/34935462 http://dx.doi.org/10.1089/crispr.2021.0087 |