Limited Expansion of Human Hepatocytes in FAH/RAG2-Deficient Swine

The mammalian liver's regenerative ability has led researchers to engineer animals as incubators for expansion of human hepatocytes. The expansion properties of human hepatocytes in immunodeficient mice are well known. However, little has been reported about larger animals that are more scalabl...

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Detalles Bibliográficos
Autores principales: Nelson, Erek David, Larson, Ellen, Joo, Dong Jin, Mao, Shennen, Glorioso, Jaime, Abu Rmilah, Anan, Zhou, Wei, Jia, Yao, Mounajjed, Taofic, Shi, Min, Bois, Melanie, Wood, Adam, Jin, Fang, Whitworth, Kristin, Wells, Kevin, Spate, Anna, Samuel, Melissa, Minshew, Anna, Walters, Eric, Rinaldo, Piero, Lillegard, Joseph B., Johnson, Aaron, Amiot, Bruce, Hickey, Raymond, Prather, Randall, Platt, Jeffrey L., Nyberg, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8892989/
https://www.ncbi.nlm.nih.gov/pubmed/34309416
http://dx.doi.org/10.1089/ten.tea.2021.0057

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