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Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation

We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of...

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Autores principales: Matsugi, Akiyoshi, Shiozaki, Tomoyuki, Tanaka, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893018/
https://www.ncbi.nlm.nih.gov/pubmed/35250830
http://dx.doi.org/10.3389/fneur.2022.826739
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author Matsugi, Akiyoshi
Shiozaki, Tomoyuki
Tanaka, Hiroaki
author_facet Matsugi, Akiyoshi
Shiozaki, Tomoyuki
Tanaka, Hiroaki
author_sort Matsugi, Akiyoshi
collection PubMed
description We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of eye motion velocity/head motion velocity to VOR-gain. The gain 60 ms after the start of head motion (VOR-gain-60 ms) and regression slope (RS) (i.e., gain in eye and head motion; VOR-gain-RS) were calculated. The total path length of the foot center of pressure (COP-TL) during upright standing was calculated to estimate body sway. Noisy Galvanic Vestibular Stimulation at 0.2, 0.6, 1.2 mA, or sham stimulation (direct current: 0 mA) was delivered to the bilateral mastoid process in random order during vHIT and COP measurements. Application of nGVS at 0.2 mA significantly reduced VOR-gain-RS, while application of nGVS at 0.6 mA significantly increased COP-TL. Vestibulo-ocular reflex-gain-60 ms differed significantly between 0.2 and 1.2 mA. There was no significant correlation between COP-TL and VOR-related parameters. These findings suggest that nGVS at 0.2 mA inhibits the VOR, while nGVS at 0.6 mA increases body sway during upright standing, although there may be no relationship between the respective effects in healthy individuals.
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spelling pubmed-88930182022-03-04 Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation Matsugi, Akiyoshi Shiozaki, Tomoyuki Tanaka, Hiroaki Front Neurol Neurology We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of eye motion velocity/head motion velocity to VOR-gain. The gain 60 ms after the start of head motion (VOR-gain-60 ms) and regression slope (RS) (i.e., gain in eye and head motion; VOR-gain-RS) were calculated. The total path length of the foot center of pressure (COP-TL) during upright standing was calculated to estimate body sway. Noisy Galvanic Vestibular Stimulation at 0.2, 0.6, 1.2 mA, or sham stimulation (direct current: 0 mA) was delivered to the bilateral mastoid process in random order during vHIT and COP measurements. Application of nGVS at 0.2 mA significantly reduced VOR-gain-RS, while application of nGVS at 0.6 mA significantly increased COP-TL. Vestibulo-ocular reflex-gain-60 ms differed significantly between 0.2 and 1.2 mA. There was no significant correlation between COP-TL and VOR-related parameters. These findings suggest that nGVS at 0.2 mA inhibits the VOR, while nGVS at 0.6 mA increases body sway during upright standing, although there may be no relationship between the respective effects in healthy individuals. Frontiers Media S.A. 2022-02-17 /pmc/articles/PMC8893018/ /pubmed/35250830 http://dx.doi.org/10.3389/fneur.2022.826739 Text en Copyright © 2022 Matsugi, Shiozaki and Tanaka. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Matsugi, Akiyoshi
Shiozaki, Tomoyuki
Tanaka, Hiroaki
Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title_full Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title_fullStr Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title_full_unstemmed Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title_short Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
title_sort vestibulo-ocular reflex is modulated by noisy galvanic vestibular stimulation
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893018/
https://www.ncbi.nlm.nih.gov/pubmed/35250830
http://dx.doi.org/10.3389/fneur.2022.826739
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