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Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation
We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893018/ https://www.ncbi.nlm.nih.gov/pubmed/35250830 http://dx.doi.org/10.3389/fneur.2022.826739 |
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author | Matsugi, Akiyoshi Shiozaki, Tomoyuki Tanaka, Hiroaki |
author_facet | Matsugi, Akiyoshi Shiozaki, Tomoyuki Tanaka, Hiroaki |
author_sort | Matsugi, Akiyoshi |
collection | PubMed |
description | We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of eye motion velocity/head motion velocity to VOR-gain. The gain 60 ms after the start of head motion (VOR-gain-60 ms) and regression slope (RS) (i.e., gain in eye and head motion; VOR-gain-RS) were calculated. The total path length of the foot center of pressure (COP-TL) during upright standing was calculated to estimate body sway. Noisy Galvanic Vestibular Stimulation at 0.2, 0.6, 1.2 mA, or sham stimulation (direct current: 0 mA) was delivered to the bilateral mastoid process in random order during vHIT and COP measurements. Application of nGVS at 0.2 mA significantly reduced VOR-gain-RS, while application of nGVS at 0.6 mA significantly increased COP-TL. Vestibulo-ocular reflex-gain-60 ms differed significantly between 0.2 and 1.2 mA. There was no significant correlation between COP-TL and VOR-related parameters. These findings suggest that nGVS at 0.2 mA inhibits the VOR, while nGVS at 0.6 mA increases body sway during upright standing, although there may be no relationship between the respective effects in healthy individuals. |
format | Online Article Text |
id | pubmed-8893018 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88930182022-03-04 Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation Matsugi, Akiyoshi Shiozaki, Tomoyuki Tanaka, Hiroaki Front Neurol Neurology We investigated whether noisy galvanic vestibular stimulation (nGVS) modulates the vestibulo-ocular reflex (VOR) and whether this effect is correlated with the effect of nGVS on body sway. Thirty healthy young adults participated. The video head impulse test (vHIT) was used to estimate the ratio of eye motion velocity/head motion velocity to VOR-gain. The gain 60 ms after the start of head motion (VOR-gain-60 ms) and regression slope (RS) (i.e., gain in eye and head motion; VOR-gain-RS) were calculated. The total path length of the foot center of pressure (COP-TL) during upright standing was calculated to estimate body sway. Noisy Galvanic Vestibular Stimulation at 0.2, 0.6, 1.2 mA, or sham stimulation (direct current: 0 mA) was delivered to the bilateral mastoid process in random order during vHIT and COP measurements. Application of nGVS at 0.2 mA significantly reduced VOR-gain-RS, while application of nGVS at 0.6 mA significantly increased COP-TL. Vestibulo-ocular reflex-gain-60 ms differed significantly between 0.2 and 1.2 mA. There was no significant correlation between COP-TL and VOR-related parameters. These findings suggest that nGVS at 0.2 mA inhibits the VOR, while nGVS at 0.6 mA increases body sway during upright standing, although there may be no relationship between the respective effects in healthy individuals. Frontiers Media S.A. 2022-02-17 /pmc/articles/PMC8893018/ /pubmed/35250830 http://dx.doi.org/10.3389/fneur.2022.826739 Text en Copyright © 2022 Matsugi, Shiozaki and Tanaka. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Matsugi, Akiyoshi Shiozaki, Tomoyuki Tanaka, Hiroaki Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title | Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title_full | Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title_fullStr | Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title_full_unstemmed | Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title_short | Vestibulo-Ocular Reflex Is Modulated by Noisy Galvanic Vestibular Stimulation |
title_sort | vestibulo-ocular reflex is modulated by noisy galvanic vestibular stimulation |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893018/ https://www.ncbi.nlm.nih.gov/pubmed/35250830 http://dx.doi.org/10.3389/fneur.2022.826739 |
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