Visualizing looping of two endogenous genomic loci using synthetic zinc‐finger proteins with anti‐FLAG and anti‐HA frankenbodies in living cells

In eukaryotic nuclei, chromatin loops mediated through cohesin are critical structures that regulate gene expression and DNA replication. Here, we demonstrate a new method to see endogenous genomic loci using synthetic zinc‐finger proteins harboring repeat epitope tags (ZF probes) for signal amplifi...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhao, Ning, Kanemaki, Masato T., Yamamoto, Yotaro, Sadamura, Yoshifusa, Ito, Yuma, Tokunaga, Makio, Stasevich, Timothy J., Kimura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893316/
https://www.ncbi.nlm.nih.gov/pubmed/34465007
http://dx.doi.org/10.1111/gtc.12893

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