H2B.V demarcates divergent strand-switch regions, some tDNA loci, and genome compartments in Trypanosoma cruzi and affects parasite differentiation and host cell invasion

Histone variants play a crucial role in chromatin structure organization and gene expression. Trypanosomatids have an unusual H2B variant (H2B.V) that is known to dimerize with the variant H2A.Z generating unstable nucleosomes. Previously, we found that H2B.V protein is enriched in tissue-derived tr...

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Detalles Bibliográficos
Autores principales: Rosón, Juliana Nunes, Vitarelli, Marcela de Oliveira, Costa-Silva, Héllida Marina, Pereira, Kamille Schmitt, Pires, David da Silva, Lopes, Leticia de Sousa, Cordeiro, Barbara, Kraus, Amelie J., Cruz, Karin Navarro Tozzi, Calderano, Simone Guedes, Fragoso, Stenio Perdigão, Siegel, T. Nicolai, Elias, Maria Carolina, da Cunha, Julia Pinheiro Chagas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893665/
https://www.ncbi.nlm.nih.gov/pubmed/35180281
http://dx.doi.org/10.1371/journal.ppat.1009694

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