Cargando…

Ameliorations in dyslipidemia and atherosclerotic plaque by the inhibition of HMG-CoA reductase and antioxidant potential of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd in rabbits

The assigned work was aimed to examine the capability of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd to inhibit HMG-CoA reductase and regression of the atherosclerotic plaque. The chemical fingerprinting of the test extract was assessed by LC-MS/MS. Consequently, the an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Charan, Jaykaran, Riyad, Priyanka, Ram, Heera, Purohit, Ashok, Ambwani, Sneha, Kashyap, Priya, Singh, Garima, Hashem, Abeer, Abd_Allah, Elsayed Fathi, Gupta, Vijai Kumar, Kumar, Ashok, Panwar, Anil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893677/ https://www.ncbi.nlm.nih.gov/pubmed/35239727 http://dx.doi.org/10.1371/journal.pone.0264646

Ejemplares similares

Correction: Ameliorations in dyslipidemia and atherosclerotic plaque by the inhibition of HMG-CoA reductase and antioxidant potential of phytoconstituents of an aqueous seed extract of Acacia senegal (L.) Willd in rabbits
por: Charan, Jaykaran, et al.
Publicado: (2022)

Phytoconstituents of an ethanolic pod extract of Prosopis cineraria triggers the inhibition of HMG-CoA reductase and the regression of atherosclerotic plaque in hypercholesterolemic rabbits
por: Ram, Heera, et al.
Publicado: (2020)

Antiatherosclerotic and Cardioprotective Potential of Acacia senegal Seeds in Diet-Induced Atherosclerosis in Rabbits
por: Ram, Heera, et al.
Publicado: (2014)

Polyploidy can Confer Superiority to West African Acacia senegal (L.) Willd. Trees
por: Diallo, Adja M., et al.
Publicado: (2016)

Toxicity and bacterial anti-motility activities of the hydroethanolic extract of Acacia senegal (L.) Willd (Fabaceae) leaves
por: Magnini, René Dofini, et al.
Publicado: (2021)

Chemical Composition and Anti-Urolithiatic Activity of Extracts from Argania spinosa (L.) Skeels Press-Cake and Acacia senegal (L.) Willd
por: El oumari, Fatima Ezzahra, et al.
Publicado: (2022)

Acacia catechu (L.f.) Willd.: A Review on Bioactive Compounds and Their Health Promoting Functionalities
por: Kumari, Monika, et al.
Publicado: (2022)

In vitro immunomodulatory potential of Artemisia indica Willd. in chicken lymphocytes
por: Ruwali, Pushpa, et al.
Publicado: (2018)

Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors
por: Samizo, Shigeyoshi, et al.
Publicado: (2023)

Pharmacological assessment of the heartwood of Acacia raddiana Willd for antifungal potential
por: Singh, Ranveer, et al.
Publicado: (2022)

Pharmacodynamic studies on the isolated active fraction of Acacia farnesiana (L.) willd
por: Kingsley, Bino, et al.
Publicado: (2014)

Pleiotropic effects of the HMG-CoA reductase inhibitors
por: Mihos, Christos G, et al.
Publicado: (2011)

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?
por: Gonzalez-Jimenez, Irene, et al.
Publicado: (2021)

Fodinicola acaciae sp. nov., an Endophytic Actinomycete Isolated from the Roots of Acacia mangium Willd. and Its Genome Analysis
por: Phạm, Huyền Thị Thanh, et al.
Publicado: (2020)

Impact of Integrated Teaching Sessions for Comprehensive Learning and Rational Pharmacotherapeutics for Medical Undergraduates
por: Ambwani, Sneha, et al.
Publicado: (2017)

Euglycemic diabetic ketoacidosis associated with SGLT2 inhibitors: A systematic review and quantitative analysis
por: Dutta, Siddhartha, et al.
Publicado: (2022)

Anti-biofilm and Antibacterial Activities of Silver Nanoparticles Synthesized by the Reducing Activity of Phytoconstituents Present in the Indian Medicinal Plants
por: Mohanta, Yugal Kishore, et al.
Publicado: (2020)

Acacia senegal gum exudate offers protection against cyclophosphamide-induced urinary bladder cytotoxicity
por: Al-Yahya, Abdulaziz A, et al.
Publicado: (2009)

Apoptotic-Induced Effects of Acacia Catechu Willd. Extract in Human Colon Cancer Cells
por: Chiaino, Elda, et al.
Publicado: (2020)

Antihyperlipidemic Activity of Aloe succotrina in Rats: Possibly Mediated by Inhibition of HMG-CoA Reductase
por: Dhingra, Dinesh, et al.
Publicado: (2014)

Corrigendum: Anti-biofilm and Antibacterial Activities of Silver Nanoparticles Synthesized by the Reducing Activity of Phytoconstituents Present in the Indian Medicinal Plants
por: Mohanta, Yugal Kishore, et al.
Publicado: (2020)

Improvements in HOMA indices and pancreatic endocrinal tissues in type 2-diabetic rats by DPP-4 inhibition and antioxidant potential of an ethanol fruit extract of Withania coagulans
por: Ram, Heera, et al.
Publicado: (2021)

The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation
por: Gelosa, Paolo, et al.
Publicado: (2007)

Positive pleiotropic effects of HMG-CoA reductase inhibitor on vitiligo
por: Noël, Martin, et al.
Publicado: (2004)

Structural and functional characterization of HMG-COA reductase from Artemisia annua
por: Kiran, Usha, et al.
Publicado: (2010)

Transcription of the three HMG-CoA reductase genes of Mucor circinelloides
por: Nagy, Gábor, et al.
Publicado: (2014)

Functional Implications of HMG-CoA Reductase Inhibition on Glucose Metabolism
por: Han, Ki Hoon
Publicado: (2018)

Chronic Onset Form of Anti-HMG-CoA Reductase Myopathy
por: Lorenzo-Villalba, Noel, et al.
Publicado: (2021)

Eupatilin Alleviates Hyperlipidemia in Mice by Inhibiting HMG-CoA Reductase
por: Kim, Kyung-Joo, et al.
Publicado: (2023)

A Review on the Main Phytoconstituents, Traditional Uses, Inventions, and Patent Literature of Gum Arabic Emphasizing Acacia seyal
por: Ashour, Mohamed A., et al.
Publicado: (2022)

LC-HRMS Profiling and Antidiabetic, Antioxidant, and Antibacterial Activities of Acacia catechu (L.f.) Willd
por: Aryal, Babita, et al.
Publicado: (2021)

Acacia catechu Willd. Extract Protects Neuronal Cells from Oxidative Stress-Induced Damage
por: Chiaino, Elda, et al.
Publicado: (2021)

The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases
por: Friesen, Jon A, et al.
Publicado: (2004)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase
por: Würtz, Peter, et al.
Publicado: (2016)

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
por: Schumacher, Marc M, et al.
Publicado: (2015)

Potential natural inhibitors of xanthine oxidase and HMG-CoA reductase in cholesterol regulation: in silico analysis
por: Marahatha, Rishab, et al.
Publicado: (2021)

High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA
por: O’Kane, Patrick T., et al.
Publicado: (2019)

Local ecological knowledge concerning the invasion of Amerindian lands in the northern Brazilian Amazon by Acacia mangium (Willd.)
por: Souza, Arlene Oliveira, et al.
Publicado: (2018)

Rangewide ploidy variation and evolution in Acacia senegal: a north–south divide?
por: Odee, David W., et al.
Publicado: (2015)

Comparative efficacy of Gum Arabic (Acacia senegal) and Tribulus terrestris on male fertility
por: Nasir, Omaima, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1hfht5lic0vtofa9791l9idjt7