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CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A Streptococcus

The control of virulence gene regulator (CovR), also called caspsule synthesis regulator (CsrR), is critical to how the major human pathogen group A Streptococcus fine-tunes virulence factor production. CovR phosphorylation (CovR~P) levels are determined by its cognate sensor kinase CovS, and functi...

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Detalles Bibliográficos
Autores principales:	Horstmann, Nicola, Myers, Kevin S., Tran, Chau Nguyen, Flores, Anthony R., Shelburne III, Samuel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893699/ https://www.ncbi.nlm.nih.gov/pubmed/35180278 http://dx.doi.org/10.1371/journal.ppat.1010341

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