microRNA-142 guards against autoimmunity by controlling T(reg) cell homeostasis and function

Regulatory T (T(reg)) cells are critical in preventing aberrant immune responses. Posttranscriptional control of gene expression by microRNA (miRNA) has recently emerged as an essential genetic element for T(reg) cell function. Here, we report that mice with T(reg) cell–specific ablation of miR-142...

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Detalles Bibliográficos
Autores principales: Wang, Wei-Le, Ouyang, Ching, Graham, Natalie M., Zhang, Yuankun, Cassady, Kaniel, Reyes, Estefany Y., Xiong, Min, Davis, Alicia M., Tang, Kathie, Zeng, Defu, Boldin, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893712/
https://www.ncbi.nlm.nih.gov/pubmed/35180231
http://dx.doi.org/10.1371/journal.pbio.3001552

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