A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer

Pharmacologic perturbation projects, such as Connectivity Map (CMap) and Library of Integrated Network-based Cellular Signatures (LINCS), have produced many perturbed expression data, providing enormous opportunities for computational therapeutic discovery. However, there is no consensus on which me...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Zhang, Hailin, Chen, Mengnuo, Wang, Siying, Qian, Ruolan, Zhang, Linmeng, Huang, Xiaowen, Wang, Jun, Liu, Zhicheng, Qin, Wenxin, Wang, Cun, Hang, Hualian, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893721/
https://www.ncbi.nlm.nih.gov/pubmed/35191375
http://dx.doi.org/10.7554/eLife.71880

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