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Characterization of a Novel Monoclonal Antibody for Serine-129 Phosphorylated α-Synuclein: A Potential Application for Clinical and Basic Research

The Lewy bodies (LBs) are the pathological hallmark of Parkinson's disease (PD). More than 90% of α-synuclein (α-syn) within LBs is phosphorylated at the serine-129 residue [pSer129 α-syn (p-α-syn)]. Although various studies have revealed that this abnormally elevated p-α-syn acts as a patholog...

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Detalles Bibliográficos
Autores principales: Liu, Weijin, Zhang, Qidi, Xing, Hao, Gao, Ge, Liu, Jia, Huang, Yue, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893957/
https://www.ncbi.nlm.nih.gov/pubmed/35250825
http://dx.doi.org/10.3389/fneur.2022.821792

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