Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?

Cryptosporidiosis has been a notifiable infection in Norway since 2012 and giardiasis since 1977. For both infections, there has been an increase in notified cases. We used a questionnaire to explore whether this may be associated with implementation of molecular diagnostic methods. We received resp...

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Autores principales: Campbell, Sophie M., Pettersen, Frank O., Brekke, Hanne, Hanevik, Kurt, Robertson, Lucy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893977/
https://www.ncbi.nlm.nih.gov/pubmed/35243573
http://dx.doi.org/10.1007/s10096-022-04426-3
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author Campbell, Sophie M.
Pettersen, Frank O.
Brekke, Hanne
Hanevik, Kurt
Robertson, Lucy J.
author_facet Campbell, Sophie M.
Pettersen, Frank O.
Brekke, Hanne
Hanevik, Kurt
Robertson, Lucy J.
author_sort Campbell, Sophie M.
collection PubMed
description Cryptosporidiosis has been a notifiable infection in Norway since 2012 and giardiasis since 1977. For both infections, there has been an increase in notified cases. We used a questionnaire to explore whether this may be associated with implementation of molecular diagnostic methods. We received responses from 14 of 16 laboratories, most of which had implemented molecular diagnostic methods for these parasites. Algorithms for testing had also been modified, and several laboratories now test more faecal samples than previously for both parasites. The increase in reported cases may reflect not only higher sensitivity of diagnostic methods, but also more sample testing. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10096-022-04426-3.
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spelling pubmed-88939772022-03-04 Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm? Campbell, Sophie M. Pettersen, Frank O. Brekke, Hanne Hanevik, Kurt Robertson, Lucy J. Eur J Clin Microbiol Infect Dis Brief Report Cryptosporidiosis has been a notifiable infection in Norway since 2012 and giardiasis since 1977. For both infections, there has been an increase in notified cases. We used a questionnaire to explore whether this may be associated with implementation of molecular diagnostic methods. We received responses from 14 of 16 laboratories, most of which had implemented molecular diagnostic methods for these parasites. Algorithms for testing had also been modified, and several laboratories now test more faecal samples than previously for both parasites. The increase in reported cases may reflect not only higher sensitivity of diagnostic methods, but also more sample testing. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10096-022-04426-3. Springer Berlin Heidelberg 2022-03-04 2022 /pmc/articles/PMC8893977/ /pubmed/35243573 http://dx.doi.org/10.1007/s10096-022-04426-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Brief Report
Campbell, Sophie M.
Pettersen, Frank O.
Brekke, Hanne
Hanevik, Kurt
Robertson, Lucy J.
Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title_full Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title_fullStr Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title_full_unstemmed Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title_short Transition to PCR diagnosis of cryptosporidiosis and giardiasis in the Norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
title_sort transition to pcr diagnosis of cryptosporidiosis and giardiasis in the norwegian healthcare system: could the increase in reported cases be due to higher sensitivity or a change in the testing algorithm?
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8893977/
https://www.ncbi.nlm.nih.gov/pubmed/35243573
http://dx.doi.org/10.1007/s10096-022-04426-3
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