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Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report

Angioimmunoblastic T‐cell lymphoma (AITL) is a type of peripheral T‐cell tumour that belongs to the group of non‐Hodgkin's lymphomas. Pulmonary lesions can be found in 7%–10% of AITL cases. Imaging findings of the lungs varied; however, immunoblastic infiltration in the lungs is rare. Our patie...

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Autores principales: Yamamoto, Gaku, Takamura, Kei, Ishida, Yuriko, Sato, Yuma, Sinozaki, Ayuka, Kikuchi, Hajime, Yamamoto, Makoto, Kobayashi, Hajime, Hirose, Naoki, Kikuchi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894012/
https://www.ncbi.nlm.nih.gov/pubmed/35280714
http://dx.doi.org/10.1002/rcr2.924
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author Yamamoto, Gaku
Takamura, Kei
Ishida, Yuriko
Sato, Yuma
Sinozaki, Ayuka
Kikuchi, Hajime
Yamamoto, Makoto
Kobayashi, Hajime
Hirose, Naoki
Kikuchi, Keisuke
author_facet Yamamoto, Gaku
Takamura, Kei
Ishida, Yuriko
Sato, Yuma
Sinozaki, Ayuka
Kikuchi, Hajime
Yamamoto, Makoto
Kobayashi, Hajime
Hirose, Naoki
Kikuchi, Keisuke
author_sort Yamamoto, Gaku
collection PubMed
description Angioimmunoblastic T‐cell lymphoma (AITL) is a type of peripheral T‐cell tumour that belongs to the group of non‐Hodgkin's lymphomas. Pulmonary lesions can be found in 7%–10% of AITL cases. Imaging findings of the lungs varied; however, immunoblastic infiltration in the lungs is rare. Our patient was a 73‐year‐old man who received repeated chemotherapy for AITL. Fourth‐line therapy using romidepsin controlled the illness, but the patient was hospitalized for dyspnoea and an infiltrative shadow. We performed bronchoalveolar lavage (BAL), and the culture was positive for Haemophilus influenzae. The patient was initially discharged with antibiotic therapy, but hospitalized again. Antibiotics were ineffective and the patient required mechanical ventilation. BAL was performed again, after which fluid cytology revealed immunoblast‐like atypical cells. Therefore, the patient was diagnosed with pulmonary infiltration due to AITL. Steroid therapy proved ineffective, and the patient died. BAL was used to effectively diagnose pulmonary AITL infiltration.
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spelling pubmed-88940122022-03-10 Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report Yamamoto, Gaku Takamura, Kei Ishida, Yuriko Sato, Yuma Sinozaki, Ayuka Kikuchi, Hajime Yamamoto, Makoto Kobayashi, Hajime Hirose, Naoki Kikuchi, Keisuke Respirol Case Rep Case Reports Angioimmunoblastic T‐cell lymphoma (AITL) is a type of peripheral T‐cell tumour that belongs to the group of non‐Hodgkin's lymphomas. Pulmonary lesions can be found in 7%–10% of AITL cases. Imaging findings of the lungs varied; however, immunoblastic infiltration in the lungs is rare. Our patient was a 73‐year‐old man who received repeated chemotherapy for AITL. Fourth‐line therapy using romidepsin controlled the illness, but the patient was hospitalized for dyspnoea and an infiltrative shadow. We performed bronchoalveolar lavage (BAL), and the culture was positive for Haemophilus influenzae. The patient was initially discharged with antibiotic therapy, but hospitalized again. Antibiotics were ineffective and the patient required mechanical ventilation. BAL was performed again, after which fluid cytology revealed immunoblast‐like atypical cells. Therefore, the patient was diagnosed with pulmonary infiltration due to AITL. Steroid therapy proved ineffective, and the patient died. BAL was used to effectively diagnose pulmonary AITL infiltration. John Wiley & Sons, Ltd 2022-03-03 /pmc/articles/PMC8894012/ /pubmed/35280714 http://dx.doi.org/10.1002/rcr2.924 Text en © 2022 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Yamamoto, Gaku
Takamura, Kei
Ishida, Yuriko
Sato, Yuma
Sinozaki, Ayuka
Kikuchi, Hajime
Yamamoto, Makoto
Kobayashi, Hajime
Hirose, Naoki
Kikuchi, Keisuke
Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title_full Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title_fullStr Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title_full_unstemmed Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title_short Use of bronchoalveolar lavage in diagnosing angioimmunoblastic T‐cell lymphoma: A case report
title_sort use of bronchoalveolar lavage in diagnosing angioimmunoblastic t‐cell lymphoma: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894012/
https://www.ncbi.nlm.nih.gov/pubmed/35280714
http://dx.doi.org/10.1002/rcr2.924
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