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Unique TLR9 Activation by Helicobacter pylori Depends on the cag T4SS, But Not on VirD2 Relaxases or VirD4 Coupling Proteins

The genomes of the gastric bacterial pathogen Helicobacter pylori harbor multiple type-IV secretion systems (T4SSs). Here we analyzed components of three T4SSs, the cytotoxin-associated genes (cag) T4SS, TFS3 and TFS4. The cag T4SS delivers the effector protein CagA and the LPS-metabolite ADP-heptos...

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Detalles Bibliográficos
Autores principales:	Tegtmeyer, Nicole, Linz, Bodo, Yamaoka, Yoshio, Backert, Steffen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894178/ https://www.ncbi.nlm.nih.gov/pubmed/35239059 http://dx.doi.org/10.1007/s00284-022-02813-9

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