c-Met-targeted chimeric antigen receptor T cells inhibit hepatocellular carcinoma cells in vitro and in vivo

c-Met is a hepatocyte growth factor receptor overexpressed in many tumors such as hepatocellular carcinoma (HCC). Therefore, c-Met may serve as a promising target for HCC immunotherapy. Modifying T cells to express c-Met-specific chimeric antigen receptor (CAR) is an attractive strategy in treating...

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Detalles Bibliográficos
Autores principales: Huang, Xiaochen, Guo, Jiaojiao, Li, Tao, Jia, Lizhou, Tang, Xiaojun, Zhu, Jin, Tang, Qi, Feng, Zhenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894281/
https://www.ncbi.nlm.nih.gov/pubmed/35403606
http://dx.doi.org/10.7555/JBR.35.20200207

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