Diagnosis of GH Deficiency Without GH Stimulation Tests

Growth hormone deficiency (GHD) is the most commonly affected pituitary hormone in childhood with a prevalence of 1 in 4000–10000 live births. GH stimulation testing (GHST) is commonly used in the diagnostic workup of GHD. However, GHD can be diagnosed in some clinical conditions without the need of...

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Detalles Bibliográficos
Autores principales: Ibba, Anastasia, Loche, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894314/
https://www.ncbi.nlm.nih.gov/pubmed/35250894
http://dx.doi.org/10.3389/fendo.2022.853290
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author Ibba, Anastasia
Loche, Sandro
author_facet Ibba, Anastasia
Loche, Sandro
author_sort Ibba, Anastasia
collection PubMed
description Growth hormone deficiency (GHD) is the most commonly affected pituitary hormone in childhood with a prevalence of 1 in 4000–10000 live births. GH stimulation testing (GHST) is commonly used in the diagnostic workup of GHD. However, GHD can be diagnosed in some clinical conditions without the need of GHST. The diagnosis of GHD in newborns does not require stimulation testing. Likewise infants/children with delayed growth and/or short stature associated with neuroradiological abnormalities and one or more additional pituitary hormone deficiencies may not need GHST. This review summarizes the current evidence on the diagnosis of GHD without stimulation tests.
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spelling pubmed-88943142022-03-05 Diagnosis of GH Deficiency Without GH Stimulation Tests Ibba, Anastasia Loche, Sandro Front Endocrinol (Lausanne) Endocrinology Growth hormone deficiency (GHD) is the most commonly affected pituitary hormone in childhood with a prevalence of 1 in 4000–10000 live births. GH stimulation testing (GHST) is commonly used in the diagnostic workup of GHD. However, GHD can be diagnosed in some clinical conditions without the need of GHST. The diagnosis of GHD in newborns does not require stimulation testing. Likewise infants/children with delayed growth and/or short stature associated with neuroradiological abnormalities and one or more additional pituitary hormone deficiencies may not need GHST. This review summarizes the current evidence on the diagnosis of GHD without stimulation tests. Frontiers Media S.A. 2022-02-18 /pmc/articles/PMC8894314/ /pubmed/35250894 http://dx.doi.org/10.3389/fendo.2022.853290 Text en Copyright © 2022 Ibba and Loche https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Ibba, Anastasia
Loche, Sandro
Diagnosis of GH Deficiency Without GH Stimulation Tests
title Diagnosis of GH Deficiency Without GH Stimulation Tests
title_full Diagnosis of GH Deficiency Without GH Stimulation Tests
title_fullStr Diagnosis of GH Deficiency Without GH Stimulation Tests
title_full_unstemmed Diagnosis of GH Deficiency Without GH Stimulation Tests
title_short Diagnosis of GH Deficiency Without GH Stimulation Tests
title_sort diagnosis of gh deficiency without gh stimulation tests
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894314/
https://www.ncbi.nlm.nih.gov/pubmed/35250894
http://dx.doi.org/10.3389/fendo.2022.853290
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