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Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration

Inherited retinal diseases (IRDs) are a group of neurodegenerative disorders that lead to photoreceptor cell death and eventually blindness. IRDs are characterised by a high genetic heterogeneity, making it imperative to design mutation-independent therapies. Mutations in a number of IRD disease gen...

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Detalles Bibliográficos
Autores principales:	Roy, Akanksha, Tolone, Arianna, Hilhorst, Riet, Groten, John, Tomar, Tushar, Paquet-Durand, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894370/ https://www.ncbi.nlm.nih.gov/pubmed/35241647 http://dx.doi.org/10.1038/s41420-022-00897-7

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