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Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia

Human papillomavirus (HPV) is detected in up to 96% of anal squamous cell cancers, where screening programs needed. However, the best methodology is still undetermined. Host DNA methylation markers CADM1, MAL and miR124 have been identified in cervical disease, but not anal disease. Anal swabs varyi...

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Detalles Bibliográficos
Autores principales: Phillips, Samuel, Cassells, Kahli, Garland, Suzanne M., Machalek, Dorothy A., Roberts, Jennifer M., Templeton, David J., Jin, Fengyi, Poynten, I. Mary, Hillman, Richard J., Grulich, Andrew E., Murray, Gerald L., Tabrizi, Sepehr N., Molano, Monica, Cornall, Alyssa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894372/
https://www.ncbi.nlm.nih.gov/pubmed/35241698
http://dx.doi.org/10.1038/s41598-022-07258-5

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