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miR-96-5p targets PTEN to mediate sunitinib resistance in clear cell renal cell carcinoma
A multiple receptor tyrosine kinase inhibitor, sunitinib, is a first-line therapy for clear cell renal cell carcinoma (CCRCC). Unfortunately, it has the major challenges of low initial response rate and resistance after about one year of treatment. Here we evaluated a microRNA (miRNA) and its target...
Autores principales: | Park, Sang Eun, Kim, Wonju, Hong, Ji-Ye, Kang, Dayeon, Park, Seulki, Suh, Jungyo, You, Dalsan, Park, Yun-Yong, Suh, Nayoung, Hwang, Jung Jin, Kim, Choung-Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894382/ https://www.ncbi.nlm.nih.gov/pubmed/35241735 http://dx.doi.org/10.1038/s41598-022-07468-x |
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