Cargando…
Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes
Currently, no oral medications are available for type 1 diabetes (T1D). While our recent randomized placebo-controlled T1D trial revealed that oral verapamil had short-term beneficial effects, their duration and underlying mechanisms remained elusive. Now, our global T1D serum proteomics analysis id...
Autores principales: | Xu, Guanlan, Grimes, Tiffany D., Grayson, Truman B., Chen, Junqin, Thielen, Lance A., Tse, Hubert M., Li, Peng, Kanke, Matt, Lin, Tai-Tu, Schepmoes, Athena A., Swensen, Adam C., Petyuk, Vladislav A., Ovalle, Fernando, Sethupathy, Praveen, Qian, Wei-Jun, Shalev, Anath |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894430/ https://www.ncbi.nlm.nih.gov/pubmed/35241690 http://dx.doi.org/10.1038/s41467-022-28826-3 |
Ejemplares similares
-
Verapamil and beta cell function in adults with recent-onset type 1 diabetes
por: Ovalle, Fernando, et al.
Publicado: (2018) -
Preventing β-Cell Loss and Diabetes With Calcium Channel Blockers
por: Xu, Guanlan, et al.
Publicado: (2012) -
Thioredoxin-interacting protein regulates insulin transcription through microRNA-204
por: Xu, Guanlan, et al.
Publicado: (2013) -
Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop
por: Jing, Gu, et al.
Publicado: (2016) -
Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes
por: Crouse, Andrew B., et al.
Publicado: (2021)