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Structural basis of leukotriene B4 receptor 1 activation

Leukotriene B4 receptor 1 (BLT1) plays crucial roles in the acute inflammatory responses and is a valuable target for anti-inflammation treatment, however, the mechanism by which leukotriene B4 (LTB4) activates receptor remains unclear. Here, we report the cryo-electron microscopy (cryo-EM) structur...

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Detalles Bibliográficos
Autores principales:	Wang, Na, He, Xinheng, Zhao, Jing, Jiang, Hualiang, Cheng, Xi, Xia, Yu, Eric Xu, H., He, Yuanzheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894450/ https://www.ncbi.nlm.nih.gov/pubmed/35241677 http://dx.doi.org/10.1038/s41467-022-28820-9

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