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Senescence and impaired DNA damage responses in alpha-synucleinopathy models

α-Synuclein is a crucial element in the pathogenesis of Parkinson’s disease (PD) and related neurological diseases. Although numerous studies have presented potential mechanisms underlying its pathogenesis, the understanding of α-synuclein-mediated neurodegeneration remains far from complete. Here,...

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Detalles Bibliográficos
Autores principales: Yoon, Ye-Seul, You, Jueng Soo, Kim, Tae-Kyung, Ahn, Woo Jung, Kim, Myoung Jun, Son, Keun Hong, Ricarte, Diadem, Ortiz, Darlene, Lee, Seung-Jae, Lee, He-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894476/
https://www.ncbi.nlm.nih.gov/pubmed/35136202
http://dx.doi.org/10.1038/s12276-022-00727-x

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