Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report

Although the incidence of hematological toxicity due to Trifluridine/tipiracil (FTD/TPI) treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events.

Detalles Bibliográficos
Autores principales: Shibutani, Masatsune, Okazaki, Yuki, Kashiwagi, Shinichiro, Nagahara, Hisashi, Fukuoka, Tatsunari, Iseki, Yasuhito, Maeda, Kiyoshi, Hirakawa, Kosei, Ohira, Masaichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894575/
https://www.ncbi.nlm.nih.gov/pubmed/35280098
http://dx.doi.org/10.1002/ccr3.5544
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author Shibutani, Masatsune
Okazaki, Yuki
Kashiwagi, Shinichiro
Nagahara, Hisashi
Fukuoka, Tatsunari
Iseki, Yasuhito
Maeda, Kiyoshi
Hirakawa, Kosei
Ohira, Masaichi
author_facet Shibutani, Masatsune
Okazaki, Yuki
Kashiwagi, Shinichiro
Nagahara, Hisashi
Fukuoka, Tatsunari
Iseki, Yasuhito
Maeda, Kiyoshi
Hirakawa, Kosei
Ohira, Masaichi
author_sort Shibutani, Masatsune
collection PubMed
description Although the incidence of hematological toxicity due to Trifluridine/tipiracil (FTD/TPI) treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events.
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spelling pubmed-88945752022-03-10 Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report Shibutani, Masatsune Okazaki, Yuki Kashiwagi, Shinichiro Nagahara, Hisashi Fukuoka, Tatsunari Iseki, Yasuhito Maeda, Kiyoshi Hirakawa, Kosei Ohira, Masaichi Clin Case Rep Case Reports Although the incidence of hematological toxicity due to Trifluridine/tipiracil (FTD/TPI) treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events. John Wiley and Sons Inc. 2022-03-03 /pmc/articles/PMC8894575/ /pubmed/35280098 http://dx.doi.org/10.1002/ccr3.5544 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Shibutani, Masatsune
Okazaki, Yuki
Kashiwagi, Shinichiro
Nagahara, Hisashi
Fukuoka, Tatsunari
Iseki, Yasuhito
Maeda, Kiyoshi
Hirakawa, Kosei
Ohira, Masaichi
Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title_full Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title_fullStr Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title_full_unstemmed Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title_short Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
title_sort severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894575/
https://www.ncbi.nlm.nih.gov/pubmed/35280098
http://dx.doi.org/10.1002/ccr3.5544
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