Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists

A polygenic risk score estimates the genetic risk of an individual for some disease or trait, calculated by aggregating the effect of many common variants associated with the condition. With the increasing availability of genetic data in large cohort studies such as the UK Biobank, inclusion of this...

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Detalles Bibliográficos
Autores principales: Collister, Jennifer A., Liu, Xiaonan, Clifton, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894758/
https://www.ncbi.nlm.nih.gov/pubmed/35251129
http://dx.doi.org/10.3389/fgene.2022.818574

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894758/
https://www.ncbi.nlm.nih.gov/pubmed/35251129
http://dx.doi.org/10.3389/fgene.2022.818574

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