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Hedgehog Suppresses Paclitaxel Sensitivity by Regulating Akt-Mediated Phosphorylation of Bax in EGFR Wild-Type Non-Small Cell Lung Cancer Cells

Non-small cell lung cancer (NSCLC) is one of the most common and deadly cancers worldwide. Among NSCLC patients, almost half have wild-type epidermal growth factor receptor (EGFR WT). The primary therapeutic option for these EGFR WT NSCLC patients is chemotherapy, while NSCLC patients with EGFR muta...

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Detalles Bibliográficos
Autores principales:	Tu, Yun-Chieh, Yeh, Wei-Chen, Yu, Hsin-Hsien, Lee, Yu-Cheng, Su, Bor-Chyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894848/ https://www.ncbi.nlm.nih.gov/pubmed/35250564 http://dx.doi.org/10.3389/fphar.2022.815308

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