Cargando…

Inflammation and immune dysfunction in Parkinson disease

Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral organs as well as the central nervous system and involves a fundamental role of neuroinflammation in its pathophysiology. Neurohistological and neuroimaging studies support the presence of ongoing and end-stage...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tansey, Malú Gámez, Wallings, Rebecca L., Houser, Madelyn C., Herrick, Mary K., Keating, Cody E., Joers, Valerie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895080/ https://www.ncbi.nlm.nih.gov/pubmed/35246670 http://dx.doi.org/10.1038/s41577-022-00684-6

Ejemplares similares

LRRK2 at the Interface Between Peripheral and Central Immune Function in Parkinson’s
por: Wallings, Rebecca L., et al.
Publicado: (2020)

Linking mitochondria to the immune response
por: Wallings, Rebecca L, et al.
Publicado: (2020)

The gut-brain axis: is intestinal inflammation a silent driver of Parkinson’s disease pathogenesis?
por: Houser, Madelyn C., et al.
Publicado: (2017)

Progranulin loss results in sex-dependent dysregulation of the peripheral and central immune system
por: Houser, Madelyn C., et al.
Publicado: (2022)

α-Synuclein and Noradrenergic Modulation of Immune Cells in Parkinson’s Disease Pathogenesis
por: Butkovich, Laura M., et al.
Publicado: (2018)

Progranulin and GPNMB: interactions in endo-lysosome function and inflammation in neurodegenerative disease
por: Gillett, Drew A., et al.
Publicado: (2023)

LRRK2 regulation of immune-pathways and inflammatory disease
por: Wallings, Rebecca L., et al.
Publicado: (2019)

Is LRRK2 the missing link between inflammatory bowel disease and Parkinson’s disease?
por: Herrick, Mary K., et al.
Publicado: (2021)

Editorial: Cannabinoids in neuroinflammation, neurodegeneration and pain: Focus on non-neuronal cells
por: Vecchiarelli, Haley A., et al.
Publicado: (2022)

Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson’s Disease
por: Kelly, Rachel, et al.
Publicado: (2020)

Experimental colitis promotes sustained, sex-dependent, T-cell-associated neuroinflammation and parkinsonian neuropathology
por: Houser, Madelyn C., et al.
Publicado: (2021)

Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson’s disease
por: Aho, Velma T. E., et al.
Publicado: (2021)

Characterization of a Cul9–Parkin double knockout mouse model for Parkinson’s disease
por: Hollville, Emilie, et al.
Publicado: (2020)

WHOPPA Enables Parallel Assessment of Leucine-Rich Repeat Kinase 2 and Glucocerebrosidase Enzymatic Activity in Parkinson’s Disease Monocytes
por: Wallings, Rebecca L., et al.
Publicado: (2022)

Editorial: Glial-targeted therapeutics for CNS disease: getting there from here
por: Tansey, Malú Gámez, et al.
Publicado: (2023)

ASO-mediated knockdown or kinase inhibition of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages
por: Wallings, Rebecca L., et al.
Publicado: (2023)

Soluble TNF mediates amyloid-independent, diet-induced alterations to immune and neuronal functions in an Alzheimer’s disease mouse model
por: MacPherson, Kathryn P., et al.
Publicado: (2023)

Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis
por: Staats, Kim A., et al.
Publicado: (2022)

Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity
por: Sanchez-Guajardo, Vanesa, et al.
Publicado: (2013)

Targeting soluble tumor necrosis factor as a potential intervention to lower risk for late-onset Alzheimer’s disease associated with obesity, metabolic syndrome, and type 2 diabetes
por: De Sousa Rodrigues, Maria Elizabeth, et al.
Publicado: (2019)

Microfluidics-free single-cell genomics reveals complex central-peripheral immune crosstalk in the mouse brain during peripheral inflammation
por: Tansey, Malú, et al.
Publicado: (2023)

Bacterial Butyrate in Parkinson's Disease Is Linked to Epigenetic Changes and Depressive Symptoms
por: Xie, Aoji, et al.
Publicado: (2022)

Cellular processes associated with LRRK2 function and dysfunction
por: Wallings, Rebecca, et al.
Publicado: (2015)

Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus
por: Bettcher, Brianne M., et al.
Publicado: (2021)

A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis
por: Boles, Jake Sondag, et al.
Publicado: (2023)

Publisher Correction: Peripheral and central immune system crosstalk in Alzheimer disease — a research prospectus
por: Bettcher, Brianne M., et al.
Publicado: (2021)

Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s disease
por: McAlpine, Fiona E, et al.
Publicado: (2008)

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease
por: McCoy, Melissa K, et al.
Publicado: (2008)

Loss of Progranulin Results in Increased Pan-Cathepsin Activity and Reduced LAMP1 Lysosomal Protein
por: Anderson, Abigail, et al.
Publicado: (2023)

Linking Glycation and Glycosylation With Inflammation and Mitochondrial Dysfunction in Parkinson’s Disease
por: Videira, Paula A. Q., et al.
Publicado: (2018)

Does neuroinflammation fan the flame in neurodegenerative diseases?
por: Frank-Cannon, Tamy C, et al.
Publicado: (2009)

The biomarkers of immune dysregulation and inflammation response in Parkinson disease
por: Chen, Li, et al.
Publicado: (2016)

LRRK2 levels in immune cells are increased in Parkinson’s disease
por: Cook, D. A., et al.
Publicado: (2017)

Central and Peripheral Inflammation: Connecting the Immune Responses of Parkinson’s Disease
por: Williams, Gregory P., et al.
Publicado: (2022)

Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe?
por: Furgiuele, Alessia, et al.
Publicado: (2023)

Visual dysfunction in Parkinson’s disease
por: Weil, Rimona S., et al.
Publicado: (2016)

Inflammation and Parkinson's Disease
por: Barcia, Carlos, et al.
Publicado: (2011)

Gustatory Dysfunction in Patients with Parkinson’s Disease
por: Jacob, Navya J., et al.
Publicado: (2023)

Emotional Dysfunction in Parkinson’s Disease
por: Blonder, Lee X., et al.
Publicado: (2011)

Mitochondrial Dysfunction in Parkinson's Disease
por: Keane, P. C., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_7b8lvtah1mo5j5ts6rh6albrr4