UNC5C Receptor Proteolytic Cleavage by Active AEP Promotes Dopaminergic Neuronal Degeneration in Parkinson's Disease

Netrin‐1 is a chemotropic cue mediating axon growth and neural migration in neuronal development, and its receptors deletion in colorectal cancer and UNC5s act as dependence receptors regulating neuronal apoptosis. Asparagine endopeptidase (AEP) is an age‐dependent protease that cuts human alpha‐syn...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Guiqin, Ahn, Eun Hee, Kang, Seong Su, Xia, Yiyuan, Liu, Xia, Zhang, Zhaohui, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895126/
https://www.ncbi.nlm.nih.gov/pubmed/35023303
http://dx.doi.org/10.1002/advs.202103396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895126/
https://www.ncbi.nlm.nih.gov/pubmed/35023303
http://dx.doi.org/10.1002/advs.202103396

Ejemplares similares